PDF(Pubmed)
Abstract：
UNASSIGNED: The correlation between diabetes and aortic dissection is not fully understood yet, although in literature many studies have suggested that there may be an association between the two conditions. The purpose of this study is to evaluate whether diabetes represents a short- and long-term risk factor for mortality from type A acute aortic dissection.
UNASSIGNED: A total of 340 patients with the diagnosis of type A acute aortic dissection underwent aortic surgery between January 2002 and March 2023. The sample was divided into 2 cohorts according to the presence of diabetes (n = 34) or not (n = 306).
UNASSIGNED: The mean age was 66 (±12.4) years and 60.9% were male. The primary endpoint was 30-day mortality. Hospital mortality was 12 (35.3%) for the diabetes group and 70 (22.9%) for nondiabetes group (P = 0.098). Overall survival at 10 years was 48.3% [95% confidence interval (CI): 41.6-54.7%], while the 10-year survival for people with diabetes was 29.5% (95% CI: 13.2-47.9%) and for nondiabetes group 50.6% (95% CI: 43.4-57.3%) (Log-rank, P = 0.024).
UNASSIGNED: Diabetes was not found to be a risk factor associated with 30-day mortality in patients undergoing surgery for type A acute aortic dissection. It was a risk factor for long-term survival, but this may be related to diabetes complications.
UNASSIGNED: A total of 340 patients with the diagnosis of type A acute aortic dissection underwent aortic surgery between January 2002 and March 2023. The sample was divided into 2 cohorts according to the presence of diabetes (n = 34) or not (n = 306).
UNASSIGNED: The mean age was 66 (±12.4) years and 60.9% were male. The primary endpoint was 30-day mortality. Hospital mortality was 12 (35.3%) for the diabetes group and 70 (22.9%) for nondiabetes group (P = 0.098). Overall survival at 10 years was 48.3% [95% confidence interval (CI): 41.6-54.7%], while the 10-year survival for people with diabetes was 29.5% (95% CI: 13.2-47.9%) and for nondiabetes group 50.6% (95% CI: 43.4-57.3%) (Log-rank, P = 0.024).
UNASSIGNED: Diabetes was not found to be a risk factor associated with 30-day mortality in patients undergoing surgery for type A acute aortic dissection. It was a risk factor for long-term survival, but this may be related to diabetes complications.
摘要：
■糖尿病与主动脉夹层之间的相关性尚未完全了解，尽管在文献中，许多研究表明这两种情况之间可能存在关联。这项研究的目的是评估糖尿病是否代表A型急性主动脉夹层死亡的短期和长期危险因素。
■在2002年1月至2023年3月期间，共有340例诊断为A型急性主动脉夹层的患者接受了主动脉手术。根据糖尿病的存在(n=34)或不存在(n=306)将样品分成2组。
■平均年龄为66（±12.4）岁，男性占60.9％。主要终点是30天死亡率。糖尿病组住院死亡率为12例（35.3%），非糖尿病组住院死亡率为70例（22.9%）（P=0.098）。10年总生存率为48.3%[95%置信区间(CI):41.6-54.7%]。糖尿病患者的10年生存率为29.5%（95%CI：13.2-47.9%），非糖尿病组的10年生存率为50.6%（95%CI：43.4-57.3%）（Log-rank，P=0.024)。
在接受A型急性主动脉夹层手术的患者中，未发现糖尿病是与30天死亡率相关的危险因素。这是长期生存的危险因素，但这可能与糖尿病并发症有关。
■在2002年1月至2023年3月期间，共有340例诊断为A型急性主动脉夹层的患者接受了主动脉手术。根据糖尿病的存在(n=34)或不存在(n=306)将样品分成2组。
■平均年龄为66（±12.4）岁，男性占60.9％。主要终点是30天死亡率。糖尿病组住院死亡率为12例（35.3%），非糖尿病组住院死亡率为70例（22.9%）（P=0.098）。10年总生存率为48.3%[95%置信区间(CI):41.6-54.7%]。糖尿病患者的10年生存率为29.5%（95%CI：13.2-47.9%），非糖尿病组的10年生存率为50.6%（95%CI：43.4-57.3%）（Log-rank，P=0.024)。
在接受A型急性主动脉夹层手术的患者中，未发现糖尿病是与30天死亡率相关的危险因素。这是长期生存的危险因素，但这可能与糖尿病并发症有关。
