Abstract：
Du Zhong is a valuable Chinese medicinal herb unique to China. It is a national second- class precious protected tree, known as \"plant gold\", which has been used to treat various diseases since ancient times. The main active ingredients are lignans, phenylprophetons, flavonoids, iridoids and steroids and terpenoids, which have pharmacological effects such as lowering blood pressure, enhancing immunity, regulating bone metabolism, protecting nerve cells, protecting liver and gallbladder and regulating blood lipids. In this paper, a comprehensive review of Eucommia ulmoides Oliv. was summarized from the processing and its compositional changes, applications, chemical components, pharmacological effects, and pharmacokinetics, and the Q-marker of Eucommia ulmoides Oliv. is preliminarily predicted from the aspects of traditional efficacy, medicinal properties and measurability of chemical composition, and the pharmacodynamic substance basis and potential Q-marker of Eucommia ulmoides Oliv. are further analyzed through network pharmacology. It is speculated that quercetin, kaempferol, β-sitosterol, chlorogenic acid and pinoresinol diglucoside components are selected as quality markers of Eucommia ulmoides Oliv., which provide a basis for the quality control evaluation and follow-up research and development of Eucommia ulmoides Oliv.
摘要：
杜仲是中国特有的名贵中草药。它是国家二级珍贵保护树，被称为“植物黄金”，自古以来就被用来治疗各种疾病。主要活性成分是木脂素，苯基先知,黄酮类化合物，环烯醚萜类和类固醇，具有降低血压等药理作用，增强免疫力,调节骨代谢，保护神经细胞,保护肝胆和调节血脂。在本文中,杜仲的全面审查。从加工及其组成变化中进行了总结，应用程序,化学成分,药理作用，和药代动力学，和杜仲的Q标记。从传统功效方面进行了初步预测，化学成分的药用特性和可测量性，以及杜仲的药效学物质基础和潜在的Q标记。通过网络药理学进一步分析。据推测槲皮素,山奈酚,β-谷甾醇，选择绿原酸和松脂醇二葡糖苷成分作为杜仲的质量标志。,为杜仲的质量控制评价和后续研发提供了依据。
