关键词: Cardiac tamponade Pleuritis Serositis Sjogren’s syndrome Thymic MALT lymphoma

Mesh : Humans Lymphoma, B-Cell, Marginal Zone / complications surgery pathology Female Adult Cardiac Tamponade / etiology surgery diagnosis Sjogren's Syndrome / complications Pleurisy / etiology Thymus Neoplasms / surgery complications pathology Postoperative Complications / etiology Thymectomy / adverse effects Prognosis Tomography, X-Ray Computed Acute Disease

来  源:   DOI:10.1186/s12957-024-03442-1   PDF(Pubmed)

Abstract:
BACKGROUND: Thymic mucosa-associated lymphoid tissue (MALT) lymphoma is rare and is known to be associated with Sjögren\'s syndrome (SjS). SjS is rarely accompanied by serositis. Here, we describe the first case of postoperative cardiac tamponade and acute pleuritis in a patient with thymic MALT lymphoma associated with SjS.
METHODS: A 33-year-old woman with SjS presented with an anterior mediastinal mass on chest computed tomography, which was performed for further examination of the condition. Suspecting a thymic MALT lymphoma or thymic epithelial tumor, total thymectomy was performed. The mediastinal mass was histopathologically diagnosed as a thymic MALT lymphoma. The patient was discharged with a good postoperative course but visited the hospital 30 days after surgery for dyspnea. Cardiac tamponade was observed and drainage was performed. Four days after pericardial drainage, chest radiography revealed massive left pleural effusion, and thoracic drainage was performed. The patient was diagnosed with serositis associated with SjS and treated with methylprednisolone, which relieved cardiac tamponade and pleuritis.
CONCLUSIONS: Surgical invasion of thymic MALT lymphomas associated with SjS may cause serositis. Postoperative follow-up should be conducted, considering the possibility of cardiac tamponade or acute pleuritis due to serositis as postoperative complications.
摘要:
背景:胸腺粘膜相关淋巴组织(MALT)淋巴瘤罕见,已知与干燥综合征(SjS)相关。SjS很少伴有浆膜炎。这里,我们描述了首例与SjS相关的胸腺MALT淋巴瘤患者术后心脏压塞和急性胸膜炎。
方法:一名33岁女性患者在胸部计算机断层扫描中表现为前纵隔肿块,这是为了进一步检查病情。怀疑胸腺MALT淋巴瘤或胸腺上皮肿瘤,进行了胸腺全切除术.纵隔肿块在组织病理学上被诊断为胸腺MALT淋巴瘤。患者术后出院,病程良好,但术后30天因呼吸困难就诊。观察到心脏填塞并进行引流。心包引流4天后,胸部X线检查显示左侧大量胸腔积液,并进行胸腔引流。该患者被诊断为与SjS相关的浆膜炎,并接受甲基强的松龙治疗,缓解了心脏压塞和胸膜炎。
结论:与SjS相关的胸腺MALT淋巴瘤的手术侵袭可能导致浆膜炎。术后应进行随访,考虑到由于浆膜炎引起的心脏填塞或急性胸膜炎作为术后并发症的可能性。
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