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Abstract：
Bizarre parosteal osteochondromatous proliferation (BPOP), also termed Nora lesion, is a rare, benign tumor most often located in the hands and feet. We herein present the second reported case of BPOP affecting the spine, an uncommon location. One year after surgical excision, the patient was pain-free and showed no evidence of recurrence. We reviewed a total of 323 cases of BPOP among 101 articles, providing the first systematic update on the latest knowledge of BPOP. The age of patients with BPOP ranges from 3 months to 87 years, peaking in the second and third decades of life. The hands are the most common location of BPOP (58.39%), followed by the feet (20.81%). Imaging features play a key role in the diagnosis of BPOP, but histopathologic diagnosis remains the gold standard. Differential diagnosis of BPOP should be based on the epidemiologic and clinical features as well as clinical examination findings. Surgical resection is the most extensively used treatment for BPOP. Recurrence is common (37.44%) and can be treated with re-excision. This article can deepen our understanding of BPOP and will be helpful for the diagnosis and treatment of BPOP in clinical practice.
摘要：
奇异的骨旁骨软骨瘤增生（BPOP），也被称为诺拉病变，是一种罕见的，良性肿瘤最常位于手和脚。我们在此介绍第二例BPOP影响脊柱的报道，一个不寻常的位置。手术切除一年后，患者无痛且无复发迹象.我们回顾了101篇文献中的323例BPOP，提供有关BPOP最新知识的首次系统更新。BPOP患者的年龄范围从3个月到87岁，在生命的第二个和第三个十年达到顶峰。双手是BPOP最常见的位置（58.39%），其次是脚(20.81%)。影像学特征在BPOP的诊断中起关键作用，但组织病理学诊断仍是金标准.BPOP的鉴别诊断应基于流行病学和临床特征以及临床检查结果。手术切除是BPOP最广泛使用的治疗方法。复发是常见的（37.44％），可以通过再次切除治疗。本文可加深对BPOP的认识,为临床上BPOP的诊断和治疗提供帮助。
