关键词: Distributed lag nonlinear model Diurnal temperature range Elderly Hospitalization Intracerebral hemorrhage Middle-aged Season

来  源:   DOI:10.4178/epih.e2024053

Abstract:
UNASSIGNED: This study investigated the seasonal impact of diurnal temperature range (DTR) on hospitalization rates for intracerebral hemorrhage (ICH) in middle-aged and elderly adults.
UNASSIGNED: We collected data on the DTR and hospitalization records of ≥45-year-old patients with ICH in 2019 in Hunan Province, central China. Time-series analyses were performed using a distributed lag nonlinear model.
UNASSIGNED: Overall, 54,690 hospitalizations for ICH were recorded. DTR showed a nonlinear relationship with ICH hospitalization in both middle-aged and elderly populations (45-59 and ≥60 years, respectively). During spring, a low DTR coupled with persistently low temperatures increased ICH risk in both age groups, while a high DTR was associated with an increased risk in the middle-aged group only (relative risk [RR], 1.24; 95% confidence interval [CI], 1.21 to 1.27). In the summer, a low DTR combined with persistently high temperatures was linked to a higher risk exclusively in the middle-aged group. A high DTR in the autumn was correlated with increased risk in both age groups. In winter, either a low DTR with a continuously low temperature or a high DTR elevated the risk solely in the elderly population (RR, 1.37; 95% CI, 1.00 to 1.69). In the elderly group, the impact of DTR on hospitalization risk manifested within a 5-day period.
UNASSIGNED: The impact of DTR on ICH hospitalization risk differed significantly across seasons and between age groups. Elderly individuals demonstrated greater sensitivity to the impact of DTR. Weather forecasting services should emphasize DTR values, and interventions targeting sensitive populations are needed.
摘要:
这项研究调查了昼夜温度范围(DTR)对中老年人脑出血(ICH)住院率的季节性影响。
我们收集了湖南省2019年≥45岁ICH患者的DTR和住院记录数据,中国中部。使用分布滞后非线性模型进行时间序列分析。
总的来说,记录了54,690例ICH住院。在中老年人群(45-59岁和≥60岁,DTR与ICH住院率呈非线性关系,分别)。在春天,低DTR加上持续的低温增加了两个年龄组的ICH风险,而较高的DTR仅与中年组的风险增加相关(相对风险[RR],1.24;95%置信区间[CI],1.21至1.27)。在夏天,仅在中年人组中,低DTR和持续高温与较高的风险相关.秋季高DTR与两个年龄组的风险增加相关。在冬天,连续低温的低DTR或高DTR仅在老年人群中升高了风险(RR,1.37;95%CI,1.00至1.69)。在老年群体中,DTR对5天内住院风险的影响。
DTR对ICH住院风险的影响在不同季节和年龄组之间存在显著差异。老年人对DTR的影响表现出更大的敏感性。天气预报服务应强调DTR值,需要针对敏感人群的干预措施。
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