UNASSIGNED: We compared epidemiological and clinical characteristics from 3 datasets: the Korea HIV/AIDS Cohort Study (dataset 1, n=1,562), retrospective cohort data (dataset 2, n=2,665), and the national HIV reporting system of the Korea Disease Control and Prevention Agency (KDCA) (dataset 3, n=17,403).
UNASSIGNED: The demographic characteristics of age, sex, and age at HIV diagnosis did not differ significantly across datasets. However, dataset 3 contained a higher percentage of patients diagnosed after 2008 (69.5%) than the other datasets. Regarding transmission routes, same-sex contact accounted for a greater proportion of dataset 1 (59.8%) compared to datasets 2 (20.9%) and 3 (32.6%). The percentage of patients with CD4 T-cell counts below 200/mm3 at HIV diagnosis was higher in datasets 1 (39.4%) and 2 (33.3%) compared to dataset 3 (16.3%). Initial HIV viral load measurements were not obtained for dataset 3.
UNASSIGNED: The Korea HIV/AIDS Cohort Study demonstrated representativeness regarding the demographic characteristics of Korean patients. Of the sources, dataset 1 contained the most data on transmission routes. While the KDCA data encompassed all HIV patients, it lacked detailed clinical information. To improve the representativeness of the Korea HIV/AIDS Cohort Study, we propose expanding and revising the cohort design and enrolling more patients who have been recently diagnosed.
■我们比较了3个数据集的流行病学和临床特征:韩国HIV/AIDS队列研究(数据集1,n=1,562),回顾性队列数据(数据集2,n=2,665),和韩国疾病控制和预防局(KDCA)的国家艾滋病毒报告系统(数据集3,n=17,403)。
■年龄的人口统计特征,性别,和HIV诊断年龄在数据集之间没有显著差异.然而,数据集3包含比其他数据集更高的2008年后诊断的患者百分比(69.5%)。关于传输路线,与数据集2(20.9%)和数据集3(32.6%)相比,同性接触在数据集1中所占的比例更高(59.8%).与数据集3(16.3%)相比,在HIV诊断中CD4T细胞计数低于200/mm3的患者百分比在数据集1(39.4%)和2(33.3%)中更高。对于数据集3,未获得初始HIV病毒载量测量。
■韩国HIV/AIDS队列研究显示了关于韩国患者的人口统计学特征的代表性。在来源中,数据集1包含最多传输路由数据。虽然KDCA数据涵盖了所有HIV患者,它缺乏详细的临床信息。为了提高韩国艾滋病毒/艾滋病队列研究的代表性,我们建议扩大和修改队列设计,并招募更多最近确诊的患者.