Abstract：
UNASSIGNED: Perianal ulcers (PAUs) related to antihemorrhoidal product use have been recently reported in the literature through a few case reports. However, other etiologies of PAU must be ruled out, including infectious disease, inflammatory disease, malignancy, pressure injuries, radiotherapy, and other topical drugs. In this report, the authors describe two cases of PAUs due to an antihemorrhoidal ointment. In case 1, a 68-year-old woman with a history of hemorrhoids presented with PAUs after using an antihemorrhoidal ointment for 2 months. The ulcers were assessed through a histopathologic study and treated with calcium alginate dressings, with complete re-epithelialization occurring after 2 months. In case 2, a 58-year-old woman with a history of hemorrhoids developed painful PAUs while using an antihemorrhoidal ointment for 2 months. No other probable cause was found, and the ulcers were treated by discontinuing the ointment. The ulcers showed marked improvement, and complete re-epithelialization occurred after 6 weeks without additional treatment.
摘要：
■与抗痔疮产品使用相关的肛周溃疡（PAU）最近已通过一些病例报告在文献中进行了报道。然而,必须排除PAU的其他病因，包括传染病,炎症性疾病，恶性肿瘤，压力伤,放射治疗,和其他外用药物。在这份报告中,作者描述了两例因抗痔疮软膏引起的PAU。在病例1中，一名68岁有痔疮病史的女性在使用抗痔疮软膏2个月后出现PAU。通过组织病理学研究评估溃疡，并用海藻酸钙敷料治疗，2个月后发生完全的再上皮化。在病例2中，一名58岁有痔疮病史的女性在使用抗痔疮软膏2个月时出现了疼痛的PAU。没有找到其他可能的原因，溃疡通过停用软膏来治疗。溃疡有明显改善,并且在没有额外治疗的情况下在6周后发生了完全的上皮再形成。
