UNASSIGNED: We searched PubMed for published studies with the Medical Subject Heading of \"intravesical chemotherapy\" and \"non-muscle invasive bladder cancer.\" The search was limited to English-language journals and full papers only. The initial search resulted in 260 articles, of which 20 relevant studies were selected.
UNASSIGNED: Five important processes were identified in the successful and efficient administration of intravesical SDC: (1) patient preparation, (2) medication procurement, (3) medication administration, (4) medication immediate aftermath, and (5) patient instruction and education. Safety precautions should be taken when handling each chemotherapy drug. A clinical pharmacist may be required for drug preparation. An important step in providing intravesical SDC is to use a closed system for the instillation of the chemo-solution. A special protocol should be adopted for every drug with its proper dwell time. The induction course consists of weekly instillation for 6 weeks. If an initial response is noted, maintenance therapy is recommended, typically monthly for 24 months.
UNASSIGNED: Successful intravesical SDC clinics necessitate appropriate patient selection, standardized workflow procedures, patient education, and good communication between the urologist, clinical pharmacists, and oncology nurses.
■我们搜索了PubMed发表的关于“膀胱内化疗”和“非肌层浸润性膀胱癌”的研究。搜索仅限于英语期刊和全文。最初的搜索结果是260篇文章,其中选择了20项相关研究。
■在成功和有效地施用膀胱内SDC中确定了五个重要过程:(1)患者准备,(2)药品采购,(3)用药管理,(4)立即用药后,(5)病人的指导和教育。处理每种化疗药物时应采取安全预防措施。药物制备可能需要临床药师。提供膀胱内SDC的重要步骤是使用封闭系统来滴注化学溶液。每种药物都应采用特殊的方案,并有适当的停留时间。诱导过程包括每周滴注6周。如果注意到初始响应,建议维持治疗,通常每月24个月。
■成功的膀胱内SDC诊所需要适当的患者选择,标准化的工作流程,患者教育,泌尿科医师之间的良好沟通,临床药师,还有肿瘤科护士.