Abstract：
OBJECTIVE: To assess acute and long-term stress in men and women after the detection of fetal anomalies leading to pregnancy termination.
METHODS: Prospective observational study.
METHODS: Tertiary referral centre for fetal medicine.
METHODS: From the initial sample of 180 pregnant women with a fetal anomaly detected by ultrasound examination, a total of 87 women terminated their pregnancy, with 72 partners included in the sample. At the time of detection, the group of women (n = 93) and their partners (n = 81) who did not terminate the pregnancy following a diagnosis were included as a comparison group.
METHODS: These women and their partners were asked to complete the Edinburgh Postnatal Depression Scale (EPDS) and the Impact of Events Scale (IES) questionnaires, both at the time of initial detection and at 6 weeks after the termination of the pregnancy.
METHODS: Responses to the EPDS and the IES at the time of initial detection and at 6 weeks after pregnancy termination.
RESULTS: Women who underwent pregnancy termination reported higher symptom levels of depression, but not traumatic stress, prior to the termination than women who chose not to terminate their pregnancy. Among men, there was a difference across depression and all subscales of traumatic stress (e.g. IES intrusion: mean difference 5.31; 95% CI 2.32-8.31). Women experienced more depressive symptoms over time than men (β = 4.33, P < 0.001) and higher symptom levels on all subscales of traumatic stress (e.g. IES intrusion: β = 5.27; P < 0.001).
CONCLUSIONS: Overall, our study underscores the heightened levels of depression and traumatic stress experienced by prospective parents, particularly prior to the decision to terminate a pregnancy following the detection of a fetal anomaly. Although women generally report more pronounced symptoms, it is noteworthy that men also experience considerable traumatic stress during this challenging time.
METHODS: Prospective observational study.
METHODS: Tertiary referral centre for fetal medicine.
METHODS: From the initial sample of 180 pregnant women with a fetal anomaly detected by ultrasound examination, a total of 87 women terminated their pregnancy, with 72 partners included in the sample. At the time of detection, the group of women (n = 93) and their partners (n = 81) who did not terminate the pregnancy following a diagnosis were included as a comparison group.
METHODS: These women and their partners were asked to complete the Edinburgh Postnatal Depression Scale (EPDS) and the Impact of Events Scale (IES) questionnaires, both at the time of initial detection and at 6 weeks after the termination of the pregnancy.
METHODS: Responses to the EPDS and the IES at the time of initial detection and at 6 weeks after pregnancy termination.
RESULTS: Women who underwent pregnancy termination reported higher symptom levels of depression, but not traumatic stress, prior to the termination than women who chose not to terminate their pregnancy. Among men, there was a difference across depression and all subscales of traumatic stress (e.g. IES intrusion: mean difference 5.31; 95% CI 2.32-8.31). Women experienced more depressive symptoms over time than men (β = 4.33, P < 0.001) and higher symptom levels on all subscales of traumatic stress (e.g. IES intrusion: β = 5.27; P < 0.001).
CONCLUSIONS: Overall, our study underscores the heightened levels of depression and traumatic stress experienced by prospective parents, particularly prior to the decision to terminate a pregnancy following the detection of a fetal anomaly. Although women generally report more pronounced symptoms, it is noteworthy that men also experience considerable traumatic stress during this challenging time.
摘要：
目的：评估男性和女性在发现胎儿异常导致终止妊娠后的急性和长期应激。
方法：前瞻性观察性研究。
方法：胎儿医学三级转诊中心。
方法：从超声检查发现胎儿异常的180名孕妇的初始样本中，共有87名妇女终止了妊娠，样本中包括72个合作伙伴。在检测的时候，纳入诊断后未终止妊娠的女性组(n=93)及其伴侣(n=81)作为对照组.
方法：要求这些妇女及其伴侣填写爱丁堡产后抑郁量表（EPDS）和事件影响量表（IES）问卷，在初次检测时和终止妊娠后6周。
方法：在初次检测时和终止妊娠后6周时对EPDS和IES的反应。
结果：终止妊娠的妇女报告抑郁症状水平较高，但不是创伤性压力，在终止妊娠之前，选择不终止妊娠的妇女。在男性中,抑郁和创伤应激的所有子量表均存在差异(例如IES侵入:平均差5.31;95%CI2.32-8.31).随着时间的推移，女性比男性经历了更多的抑郁症状（β=4.33，P<0.001），并且在所有创伤应激子量表上的症状水平更高（例如IES侵入：β=5.27；P<0.001）。
结论：总体而言，我们的研究强调了未来父母所经历的抑郁和创伤压力的加剧，特别是在检测到胎儿异常后决定终止妊娠之前。尽管女性通常会报告更明显的症状，值得注意的是，在这个充满挑战的时期，男性也经历了相当大的创伤压力。
方法：前瞻性观察性研究。
方法：胎儿医学三级转诊中心。
方法：从超声检查发现胎儿异常的180名孕妇的初始样本中，共有87名妇女终止了妊娠，样本中包括72个合作伙伴。在检测的时候，纳入诊断后未终止妊娠的女性组(n=93)及其伴侣(n=81)作为对照组.
方法：要求这些妇女及其伴侣填写爱丁堡产后抑郁量表（EPDS）和事件影响量表（IES）问卷，在初次检测时和终止妊娠后6周。
方法：在初次检测时和终止妊娠后6周时对EPDS和IES的反应。
结果：终止妊娠的妇女报告抑郁症状水平较高，但不是创伤性压力，在终止妊娠之前，选择不终止妊娠的妇女。在男性中,抑郁和创伤应激的所有子量表均存在差异(例如IES侵入:平均差5.31;95%CI2.32-8.31).随着时间的推移，女性比男性经历了更多的抑郁症状（β=4.33，P<0.001），并且在所有创伤应激子量表上的症状水平更高（例如IES侵入：β=5.27；P<0.001）。
结论：总体而言，我们的研究强调了未来父母所经历的抑郁和创伤压力的加剧，特别是在检测到胎儿异常后决定终止妊娠之前。尽管女性通常会报告更明显的症状，值得注意的是，在这个充满挑战的时期，男性也经历了相当大的创伤压力。
