PDF(Pubmed)
Abstract：
Chronic gastritis is the persistent and insidious inflammation of the gastric lining. Helicobacter pylori (H. pylori) has been identified as the most common cause of chronic gastritis and consequently elimination of H. pylori can lead to its cure. This editorial explores the use of urinary metabolic profiles before and after eradication to identify biomarkers that can aid in prognosis and treatment. Despite providing promising insights, there are limitations such as a small sample size (17 patients), a narrow treatment period of 2 wk, and treatment heterogeneity, which raise concerns. Nevertheless, these findings have opened a gateway to enhancing the treatment and prognosis of chronic gastritis through urinary metabolomics.
摘要：
慢性胃炎是胃内膜的持续和隐匿性炎症。幽门螺杆菌(H.幽门螺杆菌）已被确定为慢性胃炎的最常见原因，因此消除幽门螺杆菌可导致其治愈。这篇社论探讨了在根除之前和之后使用尿代谢谱来确定可以帮助预后和治疗的生物标志物。尽管提供了有希望的见解，有局限性，如样本量小(17名患者)，2周的狭窄治疗期，和治疗异质性，这引起了人们的关注。然而，这些发现为通过尿代谢组学提高慢性胃炎的治疗和预后打开了大门.
