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Abstract：
UNASSIGNED: Laparoscopic cholecystectomy is quite a safe procedure, as only about 2% of cases result in clinically significant postoperative complications. The occurrence of conversion and postoperative complications is associated with prolonged hospitalization and higher perioperative mortality. Some parameters assessed in preoperative laboratory tests are used to predict the risk of conversion and clinically significant postoperative complications. The aim of this study was to evaluate the usefulness of preoperative neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR) and platelets-to-lymphocyte ratio (PLR) values in predicting the risk of conversion and complications in laparoscopic cholecystectomy performed due to symptomatic cholelithiasis.
UNASSIGNED: A retrospective analysis of patients operated on for symptomatic cholelithiasis was performed. The Results of preoperative laboratory tests were assessed - NLR, MLR and PLR. Their impact on early outcomes of surgical treatment was analyzed in the study population.
UNASSIGNED: The analysis concerned 227 patients operated on for symptomatic cholelithiasis. The study group included 61 (26.9%) men and 166 (73.1%) women. As the NLR, MLR and PLR values increase, the length of hospitalization increases (rS 0.226, 0.247 and 0.181, respectively), as well as the risk of converting the procedure to an open method (p<0.05). Moreover, with increasing NLR and MLR values, the grade of postoperative complications according to the Clavien-Dindo scale increases (p 0.0001 and 0.008, respectively). The grade of postoperative complications does not depend on the PLR value.
UNASSIGNED: The risk of conversion can be assessed based on preoperative NLR, MLR and PLR values in patients undergoing surgery for symptomatic cholelithiasis. Elevated preoperative NLR and MLR values are associated with a higher grade of postoperative complications in the Clavien-Dindo scale.
UNASSIGNED: A retrospective analysis of patients operated on for symptomatic cholelithiasis was performed. The Results of preoperative laboratory tests were assessed - NLR, MLR and PLR. Their impact on early outcomes of surgical treatment was analyzed in the study population.
UNASSIGNED: The analysis concerned 227 patients operated on for symptomatic cholelithiasis. The study group included 61 (26.9%) men and 166 (73.1%) women. As the NLR, MLR and PLR values increase, the length of hospitalization increases (rS 0.226, 0.247 and 0.181, respectively), as well as the risk of converting the procedure to an open method (p<0.05). Moreover, with increasing NLR and MLR values, the grade of postoperative complications according to the Clavien-Dindo scale increases (p 0.0001 and 0.008, respectively). The grade of postoperative complications does not depend on the PLR value.
UNASSIGNED: The risk of conversion can be assessed based on preoperative NLR, MLR and PLR values in patients undergoing surgery for symptomatic cholelithiasis. Elevated preoperative NLR and MLR values are associated with a higher grade of postoperative complications in the Clavien-Dindo scale.
摘要：
■腹腔镜胆囊切除术是相当安全的手术,因为只有大约2%的病例导致临床上显著的术后并发症。转换和术后并发症的发生与住院时间延长和围手术期死亡率升高有关。在术前实验室测试中评估的一些参数用于预测转换和临床重大术后并发症的风险。这项研究的目的是评估术前中性粒细胞与淋巴细胞比率（NLR）的有用性，单核细胞与淋巴细胞比率(MLR)和血小板与淋巴细胞比率(PLR)值在预测因症状性胆石症而进行的腹腔镜胆囊切除术中的转换和并发症风险中的作用.
■对有症状的胆石症患者进行回顾性分析。评估术前实验室检查的结果-NLR，MLR和PLR。在研究人群中分析了它们对手术治疗早期结果的影响。
■该分析涉及227例因症状性胆石症而接受手术的患者。研究组包括61名（26.9％）男性和166名（73.1％）女性。作为NLR,MLR和PLR值增加，住院时间增加(rS分别为0.226、0.247和0.181)，以及将手术转换为开放方法的风险（p<0.05）。此外，随着NLR和MLR值的增加，根据Clavien-Dindo量表，术后并发症的等级增加（p分别为0.0001和0.008）。术后并发症的分级不取决于PLR值。
■可以根据术前NLR评估转换的风险，接受有症状的胆石症手术患者的MLR和PLR值。术前NLR和MLR值升高与Clavien-Dindo量表中术后并发症的分级较高相关。
■对有症状的胆石症患者进行回顾性分析。评估术前实验室检查的结果-NLR，MLR和PLR。在研究人群中分析了它们对手术治疗早期结果的影响。
■该分析涉及227例因症状性胆石症而接受手术的患者。研究组包括61名（26.9％）男性和166名（73.1％）女性。作为NLR,MLR和PLR值增加，住院时间增加(rS分别为0.226、0.247和0.181)，以及将手术转换为开放方法的风险（p<0.05）。此外，随着NLR和MLR值的增加，根据Clavien-Dindo量表，术后并发症的等级增加（p分别为0.0001和0.008）。术后并发症的分级不取决于PLR值。
■可以根据术前NLR评估转换的风险，接受有症状的胆石症手术患者的MLR和PLR值。术前NLR和MLR值升高与Clavien-Dindo量表中术后并发症的分级较高相关。
