PDF(Pubmed)
Abstract：
BACKGROUND: Ribosome profiling is a widely-used technique for measuring ribosome occupancy at nucleotide resolution. However, the need to analyze this data at nucleotide resolution introduces unique challenges in data visualization and analyses.
RESULTS: In this study, we introduce RiboGraph, a dedicated visualization tool designed to work with .ribo files, a specialized and efficient format for ribosome occupancy data. Unlike existing solutions that rely on large alignment files and time-consuming preprocessing steps, RiboGraph operates on a purpose designed compact file type. This efficiency allows for interactive, real-time visualization at ribosome-protected fragment length resolution. By providing an integrated toolset, RiboGraph empowers researchers to conduct comprehensive visual analysis of ribosome occupancy data.
METHODS: Source code, step-by-step installation instructions and links to documentation are available on GitHub: https://github.com/ribosomeprofiling/ribograph. On the same page, we provide test files and a step-by-step tutorial highlighting the key features of RiboGraph.
RESULTS: In this study, we introduce RiboGraph, a dedicated visualization tool designed to work with .ribo files, a specialized and efficient format for ribosome occupancy data. Unlike existing solutions that rely on large alignment files and time-consuming preprocessing steps, RiboGraph operates on a purpose designed compact file type. This efficiency allows for interactive, real-time visualization at ribosome-protected fragment length resolution. By providing an integrated toolset, RiboGraph empowers researchers to conduct comprehensive visual analysis of ribosome occupancy data.
METHODS: Source code, step-by-step installation instructions and links to documentation are available on GitHub: https://github.com/ribosomeprofiling/ribograph. On the same page, we provide test files and a step-by-step tutorial highlighting the key features of RiboGraph.
摘要：
背景：核糖体谱分析是一种广泛使用的技术，用于以核苷酸分辨率测量核糖体占有率。然而,以核苷酸分辨率分析这些数据的需求在数据可视化和分析中引入了独特的挑战。
结果：在这项研究中，我们介绍一下RiboGraph,一个专门的可视化工具设计的工作。ribo文件,核糖体占用数据的专门且有效的格式。与依赖大型对齐文件和耗时的预处理步骤的现有解决方案不同，RiboGraph按目的设计的紧凑文件类型运行。这种效率允许互动，核糖体保护片段长度分辨率的实时可视化。通过提供集成的工具集，RiboGraph使研究人员能够对核糖体占用数据进行全面的可视化分析。
方法：源代码，GitHub上提供了分步安装说明和文档链接：https://github.com/ribosometography/rilograph。在同一页上，我们提供了测试文件和分步教程，突出了RiboGraph的关键功能。
背景：补充数据可在Bioinformatics在线获得。
结果：在这项研究中，我们介绍一下RiboGraph,一个专门的可视化工具设计的工作。ribo文件,核糖体占用数据的专门且有效的格式。与依赖大型对齐文件和耗时的预处理步骤的现有解决方案不同，RiboGraph按目的设计的紧凑文件类型运行。这种效率允许互动，核糖体保护片段长度分辨率的实时可视化。通过提供集成的工具集，RiboGraph使研究人员能够对核糖体占用数据进行全面的可视化分析。
方法：源代码，GitHub上提供了分步安装说明和文档链接：https://github.com/ribosometography/rilograph。在同一页上，我们提供了测试文件和分步教程，突出了RiboGraph的关键功能。
背景：补充数据可在Bioinformatics在线获得。
