Abstract：
This review examines the pivotal role of photoreceptor cells in ocular refraction development, focusing on dopamine (DA) as a key neurotransmitter. Contrary to the earlier view favoring cone cells, recent studies have highlighted the substantial contributions of both rod and cone cells to the visual signaling pathways that influence ocular refractive development. Notably, rod cells appeared to play a central role. Photoreceptor cells interact intricately with circadian rhythms, color vision pathways, and other neurotransmitters, all of which are crucial for the complex mechanisms driving the development of myopia. This review emphasizes that ocular refractive development results from a coordinated interplay between diverse cell types, signaling pathways, and neurotransmitters. This perspective has significant implications for unraveling the complex mechanisms underlying myopia and aiding in the development of more effective prevention and treatment strategies.
摘要：
这篇综述探讨了感光细胞在眼屈光发展中的关键作用，专注于多巴胺（DA）作为关键的神经递质。与先前偏爱视锥细胞的观点相反，最近的研究强调了视杆和视锥细胞对影响眼屈光发育的视觉信号通路的重要贡献。值得注意的是,视杆细胞似乎起着核心作用。光感受器细胞与昼夜节律错综复杂地相互作用，彩色视觉途径，和其他神经递质，所有这些对于驱动近视发展的复杂机制至关重要。这篇综述强调，眼屈光发育是由不同细胞类型之间的协调相互作用引起的。信号通路，和神经递质。这种观点对于解开近视背后的复杂机制并帮助开发更有效的预防和治疗策略具有重要意义。
