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Abstract：
Unilateral vocal cord paralysis is frequently observed in patients who undergo thyroid surgery. This study explored the correlation between acoustic voice analysis (objective measure) and Voice Handicap Index (VHI, a self-assessment tool). One hundred and forty patients who had thyroid surgery with or without postoperative unilateral vocal cord paralysis (PVCP and NPVCP) were included. The patients were evaluated by the VHI and Dysphonia Severity Index (DSI) tools. VHI scores were significantly higher in PVCP patients than in NPVCP patients. Jitter (%) and shimmer (%) were significantly increased, whereas DSI was significantly decreased in PVCP patients. Receiver operating characteristics curve revealed that VHI scores were associated with the diagnosis of PVCP, of which VHI total score yielded an area under the curve (AUC) of 0.81. Among acoustic parameters, DSI was highly associated to PVCP (AUC=0.82, 95%CI=0.75 to 0.89). Moreover, we found a correlation between VHI scores and voice acoustic parameters. Among them, DSI had a moderate correlation with functional and VHI scores, as suggested by an R value of 0.41 and 0.49, respectively. VHI scores and acoustic parameters were associated with the diagnosis of PVCP.
摘要：
在接受甲状腺手术的患者中经常观察到单侧声带麻痹。本研究探讨了声学语音分析(客观测量)与语音障碍指数(VHI，自我评估工具)。纳入了有或没有术后单侧声带麻痹（PVCP和NPVCP）的甲状腺手术患者。通过VHI和发音障碍严重程度指数(DSI)工具对患者进行评估。PVCP患者的VHI评分明显高于NPVCP患者。抖动(%)和微光(%)显著增加，而PVCP患者的DSI显著降低。受试者工作特征曲线显示VHI评分与PVCP的诊断相关,其中VHI总分的曲线下面积（AUC）为0.81。在声学参数中，DSI与PVCP高度相关（AUC=0.82，95CI=0.75至0.89）。此外，我们发现VHI评分与语音声学参数之间存在相关性.其中,DSI与功能和VHI评分有中等相关性，R值分别为0.41和0.49。VHI评分和声学参数与PVCP的诊断相关。
