Abstract:
In this paper, we review the value of phantoms for body MRI in the context of their uses for quantitative MRI methods research, clinical trials, and clinical imaging. Certain uses of phantoms are common throughout the body MRI community, including measuring bias, assessing reproducibility, and training. In addition to these uses, phantoms in body MRI methods research are used for novel methods development and the design of motion compensation and mitigation techniques. For clinical trials, phantoms are an essential part of quality management strategies, facilitating the conduct of ethically sound, reliable, and regulatorily compliant clinical research of both novel MRI methods and therapeutic agents. In the clinic, phantoms are used for development of protocols, mitigation of cost, quality control, and radiotherapy. We briefly review phantoms developed for quantitative body MRI, and finally, we review open questions regarding the most effective use of a phantom for body MRI.
摘要:
在本文中,我们在定量MRI方法研究中使用体模对身体MRI的价值,临床试验,和临床成像。幻影的某些用途在整个身体MRI社区中很常见,包括测量偏差,评估再现性,和训练。除了这些用途,人体MRI方法研究中的体模用于新方法的开发以及运动补偿和缓解技术的设计。对于临床试验,幻影是质量管理战略的重要组成部分,促进道德健全的行为,可靠,以及新型MRI方法和治疗剂的规律性临床研究。在诊所里,幻影用于协议的开发,降低成本,质量控制,和放射治疗。我们简要回顾了为定量人体MRI开发的体模,最后,我们回顾了关于最有效地使用体模进行身体MRI的悬而未决的问题。