关键词: Differential diagnosis Follicular dendritic cell sarcoma Parotid gland Salivary gland

Mesh : Humans Dendritic Cell Sarcoma, Follicular / pathology Female Parotid Neoplasms / pathology Middle Aged Biomarkers, Tumor / analysis

来  源:   DOI:10.1007/s12105-024-01659-w   PDF(Pubmed)

Abstract:
Follicular dendritic cell sarcoma of the parotid gland is an extremely rare tumor, with only six cases reported in the literature. A 51-year-old female had a 3.0 cm tumor resected from the right parotid gland. The tumor exhibited solid sheets, whorls, fascicular pattern, and syncytium appearance with an indistinct cell border. The lymphocytic infiltrate was sprinkled throughout the neoplasm, with focal prominent perivascular cuffing. Immunohistochemically, it was positive for follicular dendritic cell markers CD21, CD23, and CD35. We aim to enhance the understanding of this neoplasm and alert pathologists to this rare entity in this region to avoid misdiagnosis.
摘要:
腮腺的滤泡树突状细胞肉瘤是一种极其罕见的肿瘤,文献中只报道了6例。一名51岁的女性从右侧腮腺切除了3.0厘米的肿瘤。肿瘤表现出坚实的薄片,螺纹,束状图案,和合胞体外观,细胞边界模糊。淋巴细胞浸润散布在整个肿瘤中,局灶性明显的血管周围袖口。免疫组织化学,滤泡树突状细胞标志物CD21,CD23和CD35呈阳性.我们旨在增强对这种肿瘤的了解,并提醒病理学家注意该地区的这种罕见实体,以避免误诊。
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