Abstract：
The harsh environment of diabetic wounds, including bacterial infection and wound hypoxia, is not conducive to wound healing. Herein, an enzyme-like photocatalytic octahedral Rh/Ag2MoO4 is developed to manage diabetic-infected wounds. The introduction of Rh nanoparticles with catalase-like catalytic activity can enhance the photothermal conversion and photocatalytic performance of Rh/Ag2MoO4 by improving near-infrared absorbance and promoting the separation of electron-hole pairs, respectively. Rh/Ag2MoO4 can effectively eliminate pathogens through a combination of photothermal and photocatalytic antibacterial therapy. After bacteria inactivation, Rh/Ag2MoO4 can catalyze hydrogen peroxide to produce oxygen to alleviate the hypoxic environment of diabetic wounds. The in vivo treatment effect demonstrated the excellent therapeutic performance of Rh/Ag2MoO4 on diabetic infected wounds by removing infectious pathogens and relieving oxygen deficiency, confirming the potential application of Rh/Ag2MoO4 in the treatment of diabetic infected wounds.
摘要：
糖尿病伤口的恶劣环境，包括细菌感染和伤口缺氧，不利于伤口愈合。在这里，开发了一种类似酶的光催化八面体Rh/Ag2MoO4来管理糖尿病感染的伤口。具有过氧化氢酶样催化活性的Rh纳米粒子的引入可以通过改善近红外吸收和促进电子-空穴对的分离来增强Rh/Ag2MoO4的光热转化和光催化性能,分别。Rh/Ag2MoO4可以通过光热和光催化抗菌疗法的结合有效消除病原体。细菌灭活后,Rh/Ag2MoO4可以催化过氧化氢产生氧气，缓解糖尿病创面的缺氧环境。体内治疗效果证明了Rh/Ag2MoO4通过去除感染性病原体和缓解缺氧对糖尿病感染伤口的优异治疗性能。证实了Rh/Ag2MoO4在治疗糖尿病感染伤口中的潜在应用。
