PDF(Pubmed)
Abstract：
UNASSIGNED: Mvolo in Western Equatoria of South Sudan has been a hotspot for Onchocerca volvulus transmission since the 1940s. In Mvolo onchocerciasis is a disease of public health importance, associated with onchocerciasis-associated epilepsy including nodding syndrome.
UNASSIGNED: We conducted an entomological study to map the breeding sites of blackflies (Simulium damnosum, sensu lato) on the river Naam, to allow the removal of vegetation from vector breeding sites, the \"slash and clear\". Three blackfly catching sites were established along the river. Focus group discussions were also conducted to assess the willingness of the communities to support the \"slash and clear\" intervention and the semi-annual distribution of ivermectin.
UNASSIGNED: A total of 2466 female S. damnosum s.l. were caught in 14×11h (06.00-15.00) catches. The highest biting density of 4210.25 flies/month/h and monthly biting rate (MBR) of 11,482.25 bites/man/month were observed in November 2023. Biting density and MBR reduced to zero in the intervention site by April 2024. While the mean parity rate was 31% (CI: 0.2976±0.9176). Two diurnal biting peaks were observed, one from 9:00-10:00 (at the bridge site) and a prominent one from 14:00-15:00 in the two catching sites in Mvolo. Along the river Naam, only one site was found productive for S. damnosum s.l.; and the larvae and adults were morphologically associated with the anthropophilic S. damnosum. The \"slash and clear\" intervention was implemented at Dogoyabolu along the river Naam. Communities expressed willingness to support a \"slash and clear\" intervention and the semi-annual distribution of ivermectin.
UNASSIGNED: S. damnosum active breeding was identified along the river Naam in a stretch of 3-5 km close to human settlements. Highest blackfly biting density was 4210.25 flies/month/h, and two fly biting peaks were observed. A community \"slash and clear\" vector control was implemented, and will be prospectively monitored.
UNASSIGNED: We conducted an entomological study to map the breeding sites of blackflies (Simulium damnosum, sensu lato) on the river Naam, to allow the removal of vegetation from vector breeding sites, the \"slash and clear\". Three blackfly catching sites were established along the river. Focus group discussions were also conducted to assess the willingness of the communities to support the \"slash and clear\" intervention and the semi-annual distribution of ivermectin.
UNASSIGNED: A total of 2466 female S. damnosum s.l. were caught in 14×11h (06.00-15.00) catches. The highest biting density of 4210.25 flies/month/h and monthly biting rate (MBR) of 11,482.25 bites/man/month were observed in November 2023. Biting density and MBR reduced to zero in the intervention site by April 2024. While the mean parity rate was 31% (CI: 0.2976±0.9176). Two diurnal biting peaks were observed, one from 9:00-10:00 (at the bridge site) and a prominent one from 14:00-15:00 in the two catching sites in Mvolo. Along the river Naam, only one site was found productive for S. damnosum s.l.; and the larvae and adults were morphologically associated with the anthropophilic S. damnosum. The \"slash and clear\" intervention was implemented at Dogoyabolu along the river Naam. Communities expressed willingness to support a \"slash and clear\" intervention and the semi-annual distribution of ivermectin.
UNASSIGNED: S. damnosum active breeding was identified along the river Naam in a stretch of 3-5 km close to human settlements. Highest blackfly biting density was 4210.25 flies/month/h, and two fly biting peaks were observed. A community \"slash and clear\" vector control was implemented, and will be prospectively monitored.
摘要：
■自1940年代以来，南苏丹西赤道州的Mvolo一直是Onchocerca扭转传播的热点。在Mvolo，盘尾丝虫病是一种具有公共卫生重要性的疾病，与盘尾丝虫病相关的癫痫，包括点头综合征。
■我们进行了昆虫学研究，以绘制黑蝇的繁殖地图（Simuliumdamnosum，sensulato)在Naam河上，为了清除病媒繁殖地的植被，“斜杠和清除”。沿河建立了三个黑蝇捕集点。还进行了焦点小组讨论，以评估社区支持“斜切和明确”干预措施和伊维菌素半年分布的意愿。
■共有2466名雌性S.damnosums.l.被捕获在14×11h（06.00-15.00）的渔获量中。2023年11月观察到最高的叮咬密度为410.25只苍蝇/月/h，每月叮咬率（MBR）为11,482.25只/人/月。到2024年4月，干预地点的咬密度和MBR降至零。平均奇偶校验率为31%(CI:0.2976±0.9176)。观察到两个昼夜叮咬峰，一个在9:00-10:00（在桥上），一个在14:00-15:00在Mvolo的两个捕获地点突出。沿着Naam河，只有一个地点被发现对S.damnosums.l.有生产力；幼虫和成虫在形态上与嗜人S.damnosum相关。在Naam河沿岸的Dogoyabolu实施了“斜杠和清除”干预措施。社区表示愿意支持“斜线和明确”干预措施以及伊维菌素的半年度分发。
■S.在靠近人类住区的3-5公里处，沿着Naam河发现了damnosum活跃的繁殖。最高的黑蝇叮咬密度为422.25蝇/月/h，并观察到两个咬蝇峰。实施了社区“斜线和清除”矢量控制，并将进行前瞻性监测。
■我们进行了昆虫学研究，以绘制黑蝇的繁殖地图（Simuliumdamnosum，sensulato)在Naam河上，为了清除病媒繁殖地的植被，“斜杠和清除”。沿河建立了三个黑蝇捕集点。还进行了焦点小组讨论，以评估社区支持“斜切和明确”干预措施和伊维菌素半年分布的意愿。
■共有2466名雌性S.damnosums.l.被捕获在14×11h（06.00-15.00）的渔获量中。2023年11月观察到最高的叮咬密度为410.25只苍蝇/月/h，每月叮咬率（MBR）为11,482.25只/人/月。到2024年4月，干预地点的咬密度和MBR降至零。平均奇偶校验率为31%(CI:0.2976±0.9176)。观察到两个昼夜叮咬峰，一个在9:00-10:00（在桥上），一个在14:00-15:00在Mvolo的两个捕获地点突出。沿着Naam河，只有一个地点被发现对S.damnosums.l.有生产力；幼虫和成虫在形态上与嗜人S.damnosum相关。在Naam河沿岸的Dogoyabolu实施了“斜杠和清除”干预措施。社区表示愿意支持“斜线和明确”干预措施以及伊维菌素的半年度分发。
■S.在靠近人类住区的3-5公里处，沿着Naam河发现了damnosum活跃的繁殖。最高的黑蝇叮咬密度为422.25蝇/月/h，并观察到两个咬蝇峰。实施了社区“斜线和清除”矢量控制，并将进行前瞻性监测。
