PDF(Pubmed)
Abstract：
Moyamoya angiopathy is a rare cerebrovascular condition characterized by insufficient cerebral blood flow resulting from arterial vessel narrowing or occlusion, potentially leading to cerebral ischemia due to inadequate oxygen and nutrient supply to the brain tissue. The development of collateral vessels in stenotic regions, inherently fragile and prone to rupture, may further precipitate intracerebral hemorrhage. Alongside focal neurological symptoms, the common clinical presentations of Moyamoya angiopathy encompass headaches, dizziness, cognitive impairments, seizures, and involuntary movements. When associated with an underlying systemic illness, including Down Syndrome, cranial radiation, neurofibromatosis type 1, or meningitis, the condition is termed Moyamoya syndrome; whereas when idiopathic and a genetic mutation are identified, it is referred to as Moyamoya disease. In this report, we present a case of the rare Moyamoya syndrome, which was attributed to syphilis and HIV infection and was identified during an investigation into the etiology of ischemic stroke in a young patient.
摘要：
Moyamoya血管病是一种罕见的脑血管疾病，其特征是动脉狭窄或闭塞导致脑血流量不足。由于脑组织的氧气和营养供应不足，可能导致脑缺血。狭窄区域侧支血管的发育，天生脆弱，容易破裂，可能进一步导致脑出血。除了局灶性神经症状，烟雾血管病的常见临床表现包括头痛，头晕,认知障碍，癫痫发作,和非自愿的运动。当与潜在的系统性疾病相关时，包括唐氏综合症,头颅放射,神经纤维瘤病1型，或脑膜炎，这种情况被称为烟雾综合征；而当特发性和基因突变被识别时，它被称为烟雾病。在这份报告中,我们介绍了一例罕见的烟雾综合症,这归因于梅毒和HIV感染，并在对年轻患者缺血性卒中病因的调查中被发现。
