PDF(Pubmed)
Abstract：
To translate near-infrared (NIR) and shortwave infrared (SWIR) fluorescence imaging into the clinic, the paired imaging device needs to detect trace doses of fluorescent imaging agents. Except for the filtration scheme and excitation light source, the image sensor used will finally determine the detection limitations of NIR and SWIR fluorescence imaging systems. In this review, we investigate the current state-of-the-art image sensors used in NIR and SWIR fluorescence imaging systems and discuss the advantages and limitations of their characteristics, such as readout architecture and noise factors. Finally, the imaging performance of these image sensors is evaluated and compared.
摘要：
为了将近红外（NIR）和短波红外（SWIR）荧光成像应用于临床，成对的成像设备需要检测痕量剂量的荧光成像剂。除过滤方案和激发光源外，使用的图像传感器将最终确定NIR和SWIR荧光成像系统的检测限制。在这次审查中,我们研究了当前用于近红外和近红外荧光成像系统的最先进的图像传感器，并讨论了其特性的优点和局限性，如读出结构和噪声因素。最后,对这些图像传感器的成像性能进行评估和比较。
