PDF(Pubmed)
Abstract：
This is a single tertiary population-based study conducted at a center in southwest Romania. We retrospectively compared data obtained in two periods: January 2008-December 2013 and January 2018-December 2023. The global incidence of the transposition of great arteries in terminated cases, in addition to those resulting in live-born pregnancies, remained almost constant. The live-birth incidence decreased. The median gestational age at diagnosis decreased from 29.3 gestational weeks (mean 25.4) to 13.4 weeks (mean 17.2). The second trimester and the overall detection rate in the prenatal period did not significantly change, but the increase was statistically significant in the first trimester. The proportion of terminated pregnancies in fetuses diagnosed with the transposition of great arteries significantly increased (14.28% to 75%, p = 0.019).
摘要：
这是在罗马尼亚西南部的一个中心进行的基于人口的单一三级研究。我们回顾性比较了2008年1月至2013年12月和2018年1月至2023年12月两个时期的数据。在终止病例中大动脉转位的全球发病率，除了那些导致活产怀孕的人，几乎保持不变。活产发生率下降。诊断时的中位孕龄从29.3孕周（平均25.4周）下降到13.4周（平均17.2周）。孕中期和产前总体检出率无明显变化,但在妊娠早期，这种增加具有统计学意义。诊断为大动脉转位的胎儿中终止妊娠的比例显着增加（14.28％至75％，p=0.019)。
