PDF(Pubmed)
Abstract：
Peyronie\'s disease (PD) affects the penile albuginea, resulting in penile deformity, pain, erectile dysfunction (ED), and an anxious-depressive state. PD diagnosis involves a thorough medical history, penile palpation, documentation of the penile deformation, a dynamic penile echo color Doppler ultrasound (PCDU), and the completion of questionnaires for the evaluation of pain, ED, and psychometric tests. The aim of this study was to evaluate the symptoms of PD and their prevalence in PD patients in the active phase who had access to our andrology clinic. Inclusion criteria: availability of data on patients diagnosed with PD, including detailed medical history, blood tests, penile palpation, photographic documentation of penile deformity, and penile PCDU. Exclusion criteria: PD patients in the stable phase or those without the specified tests and data mentioned above. Our study found a higher prevalence of PD in younger patients (24.2%), a higher coexistence of PD with chronic prostatitis (35.6%), a higher percentage of cases of association between penile deformity and penile curvature (84.4%), a higher prevalence of \"significant anxiety\" (88.4%), a higher presence of plaque calcification (35.6%), and the detection of a longer duration of the first phase of PD (>18 months). The most frequently observed type of penile curvature was dorsal, followed by left lateral, right lateral, and, less commonly, ventral. We observed a significant statistical correlation between patient age and IIEF score, indicating that patients over the age of 40 years are at a higher risk of experiencing ED. We found a strong statistical relationship between VAS score and age. As age increases, the VAS score decreases, suggesting that younger patients reported more penile pain compared to those who were older than 40 years. Furthermore, we found that penile pain has a significant impact on the psychological state of PD patients. We also found that 38.8% of PD patients suffered from severe anxiety. In relation to this, psychotherapy should be integrated into PD treatment to improve the quality of life and treatment adherence.
摘要：
佩罗尼病（PD）影响阴茎白膜，导致阴茎畸形，疼痛,勃起功能障碍（ED），和焦虑抑郁状态。PD诊断涉及全面的病史，阴茎触诊,阴茎变形的文件，动态阴茎回波彩色多普勒超声（PCDU），以及完成疼痛评估问卷，ED,和心理测试。这项研究的目的是评估进入我们男科诊所的活动期PD患者的PD症状及其患病率。纳入标准：诊断为PD的患者的数据可用性，包括详细的病史,验血,阴茎触诊,阴茎畸形的摄影文档，和阴茎PCDU。排除标准：处于稳定期的PD患者或没有上述指定测试和数据的患者。我们的研究发现，年轻患者的PD患病率更高(24.2%)，PD与慢性前列腺炎的共存率较高（35.6％），阴茎畸形与阴茎弯曲相关的病例比例较高(84.4%)，“显著焦虑”的患病率较高(88.4%)，斑块钙化的发生率较高（35.6%），并检测到持续时间较长的第一阶段PD（>18个月）。最常见的阴茎弯曲类型是背侧，其次是左侧，右侧,and,不太常见，腹侧。我们观察到患者年龄和IIEF评分之间存在显著的统计学相关性，表明40岁以上的患者患ED的风险较高。我们发现VAS评分和年龄之间有很强的统计关系。随着年龄的增长,VAS评分降低，这表明与40岁以上的患者相比，年轻患者报告的阴茎疼痛更多。此外，我们发现阴茎疼痛对PD患者的心理状态有显著影响。我们还发现38.8%的PD患者患有严重的焦虑。关于这一点,应将心理治疗纳入PD治疗，以改善生活质量和治疗依从性。
