Abstract:
Ultra-wide-field optical coherence tomography (UWF-OCT) has been recently introduced into clinical ophthalmological practice. To date, there are few data on the reference values of the retinal thickness (RT) and choroidal thickness (CT) measured with this technique. This study aimed to analyze the variance in RT and CT in the healthy eyes of white Caucasian patients with UWF-OCT tests performed with the largest available scan size of 23 × 20 mm. The data were analyzed with reference to the patients\' age and gender and the axial length of the eyeball. The results of UWF-OCT scanning enabled us to visualize the shape of the retina and choroid in a large portion of the eyeball. Both anatomical entities became significantly thinner at the periphery. The peripheral CT was greater in the upper and temporal sectors; the RT was higher in the nasal compared to the temporal sectors. Both the choroid and retina showed a reduced thickness with age; however, the CT and RT did not show a statistically significant correlation with the axial length after adjusting for age and gender. Age-related variations in thickness were especially prominent in the choroid. The CT in UWF-OCT testing was significantly greater in females, while the RT was greater in males. UWF-OCT testing provides additional information on the anatomical structure of the retina and choroid compared to standard-field OCT.
摘要:
最近,超宽场光学相干断层扫描(UWF-OCT)已被引入临床眼科实践。迄今为止,使用该技术测量的视网膜厚度(RT)和脉络膜厚度(CT)的参考值数据很少。这项研究旨在分析白色白人患者健康眼睛的RT和CT差异,并进行了最大可用扫描尺寸为23×20mm的UWF-OCT测试。参考患者的年龄和性别以及眼球的轴向长度对数据进行分析。UWF-OCT扫描的结果使我们能够可视化大部分眼球中的视网膜和脉络膜的形状。两个解剖实体在外围都变得明显变薄。上部和颞部的周围CT更大;与颞部相比,鼻部的RT更高。脉络膜和视网膜都显示出随着年龄的增长厚度减少;然而,校正年龄和性别后,CT和RT与眼轴长度无统计学意义的相关性.与年龄相关的厚度变化在脉络膜中尤为突出。女性UWF-OCT检查中的CT明显增高,而男性的RT更大。与标准视野OCT相比,UWF-OCT测试提供了有关视网膜和脉络膜解剖结构的其他信息。