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Abstract：
Background: In burn care, achieving swift healing with minimal complications remains paramount. This investigation assesses the role of polyhexamethylene biguanide (PHMB) in managing pediatric superficial partial-thickness burns, focusing on the effects of various patient-specific factors on recovery. Methods: Through a retrospective analysis of 27 pediatric cases treated with PHMB, we evaluated the impact of age, burn size, dressing frequency, treatment delay, cold therapy application, and analgesic usage on the time until reepithelialization (TTRE). Results: The majority of patients benefited from early cold therapy, yet only 1 in 3 patients received analgesics. A mean healing time of 8.78 (SD: 2.64) days was observed, with the extent of the burn showing a strong correlation (r: 0.63) to TTRE. Most treatments were managed outpatient, evidenced by a negligible average hospital stay (0.96 days), with recorded no complications. Conclusions: Our findings endorse PHMB as a promising treatment for superficial second-degree burns in young patients, due to the observed stable and rapid wound closure without the association of increased risks. Continued exploration into the optimal application of prehospital interventions and the comprehensive benefits of PHMB in pediatric burn management is necessary. Future research should assess long-term outcomes, including functionality, scar quality, and patient satisfaction.
摘要：
背景：在烧伤护理中，以最小的并发症实现快速愈合仍然是至关重要的。这项研究评估了聚六亚甲基双胍（PHMB）在治疗小儿浅表部分厚度烧伤中的作用，关注各种患者特定因素对康复的影响。方法:通过对27例PHMB患儿的临床资料进行回顾性分析,我们评估了年龄的影响，燃烧尺寸,敷料频率，治疗延迟，冷疗应用，和镇痛的使用时间，直到上皮形成（TTRE）。结果：大多数患者受益于早期冷疗，然而,只有1/3的患者接受了镇痛药.平均愈合时间为8.78（SD：2.64）天，烧伤程度与TTRE有很强的相关性(r:0.63)。大多数治疗都是门诊治疗，平均住院时间微不足道(0.96天)，记录无并发症。结论：我们的发现认可PHMB是年轻患者浅表二度烧伤的有希望的治疗方法，由于观察到稳定和快速的伤口闭合，而没有增加的风险。继续探索院前干预措施的最佳应用以及PHMB在小儿烧伤管理中的综合效益是必要的。未来的研究应该评估长期结果，包括功能，疤痕质量，患者满意度。
