PDF(Pubmed)
Abstract：
Background/Objectives: Catecholamines are among those agents that are indispensable in modern intensive care medicine. The rapid availability of hygienically impeccable and correctly concentrated injectable solutions, e.g., for syringe pumps, is becoming more and more important. However, little research has been conducted regarding how the use of catecholamines is distributed in different wards and what options can be used to achieve optimal availability. Methods: In a retrospective monocentric study from 2019 to 2022, all continuously applied catecholamines in intensive care units (ICU) and intermediate care units (IMC) were investigated. The focus was on potential optimization by utilizing manufactured ready-to-administer solutions in the context of the economization of patient care. Results: Norepinephrine syringes represented 81% of all syringes administered, appearing to be the most frequently used on all wards. Production by the in-house pharmacy showed both financial advantages and an increase in patient safety compared to syringes produced at the bedside. Discussion: Increasing numbers of critically ill patients coupled with growing staff shortages and an increased awareness of safety requirements are driving the move towards ready-to-use and ready-to-administer solutions in critical care medicine. In-house manufacturing by hospital pharmacies can be a promising option to optimize processes and improve the economics of patient care. Conclusions: Individual calculations of the required catecholamine preparations with regard to possible economic advantages should be carried out in hospitals. In particular, in-house production of ready-to-use and ready-to-administer preparations could significantly increase patient safety and seems to be economically viable.
摘要：
背景/目的：儿茶酚胺是现代重症监护医学中不可或缺的药物之一。快速获得卫生上无可挑剔且正确浓缩的可注射溶液，例如，对于注射泵，变得越来越重要。然而,关于儿茶酚胺的使用如何在不同病房中分布以及可以使用哪些选择来实现最佳可用性的研究很少。方法：在2019年至2022年的一项回顾性单中心研究中，对所有在重症监护病房（ICU）和中间监护病房（IMC）中连续应用儿茶酚胺进行了调查。重点是在节省患者护理的背景下，通过利用制造的随时可用的解决方案进行潜在优化。结果：去甲肾上腺素注射器占所有注射器的81%，似乎是所有病房最常用的。与床边生产的注射器相比，内部药房的生产显示出财务优势和患者安全性的提高。讨论：越来越多的危重病人加上人员短缺的增加和对安全要求的认识的提高，正在推动重症监护医学中的现成和现成的管理解决方案。医院药房的内部制造可能是优化流程和提高患者护理经济性的有希望的选择。结论：应在医院中对所需的儿茶酚胺制剂进行有关可能的经济优势的单独计算。特别是,内部生产的即用型和即用型制剂可以显著提高患者的安全性,而且似乎在经济上是可行的.
