PDF(Pubmed)
Abstract：
Background/Objectives: As heart failure (HF) patients face increased vulnerability to respiratory infections, optimizing pneumococcal and influenza vaccination coverage becomes pivotal for mitigating additional health risks and reducing hospitalizations, morbidity, and mortality rates within this population. In this specific subpopulation of patients, vaccination coverage for pneumococcal and influenza holds heightened significance compared to other vaccines due to their susceptibility to respiratory infections, which can exacerbate existing cardiovascular conditions and lead to severe complications or even death. However, despite the recognized benefits, vaccination coverage among HF patients remains below expectations. The aim of the present systematic review was to assess the vaccination coverage for influenza and pneumococcus in HF patients from 2005 to 2023 and the vaccination\'s effects on survival and hospitalizations. Methods: The authors developed the protocol of the review in accordance with the PRISMA guidelines, and the search was performed in databases including PubMed and Scopus. After the initial search, 851 studies were found in PubMed Library and 1961 in Scopus (total of 2812 studies). Results: After the initial evaluation, 23 publications were finally included in the analysis. The total study population consisted of 6,093,497 participants. Regarding the influenza vaccine, vaccination coverage ranged from low rates of 2.5% to very high rates of 97%, while the respective pneumococcal vaccination coverage ranged from 20% to 84.6%. Most studies demonstrated a beneficial effect of vaccination on survival and hospitalizations. Conclusions: The present systematic review study showed a wide variety of vaccination coverage among patients with heart failure.
摘要：
背景/目标：由于心力衰竭（HF）患者面临呼吸道感染的脆弱性增加，优化肺炎球菌和流感疫苗接种覆盖率对于减轻额外的健康风险和减少住院至关重要，发病率，以及该人群的死亡率。在这个特定的患者亚群中，与其他疫苗相比，肺炎球菌和流感的疫苗接种覆盖率因其对呼吸道感染的易感性而具有更高的意义，这可能会加剧现有的心血管疾病，并导致严重的并发症甚至死亡。然而,尽管有公认的好处，HF患者的疫苗接种覆盖率仍低于预期.本系统评价的目的是评估2005年至2023年HF患者流感和肺炎球菌的疫苗接种覆盖率以及疫苗接种对生存和住院的影响。方法：作者根据PRISMA指南制定了审查方案，并且在包括PubMed和Scopus在内的数据库中进行搜索。在最初的搜索之后,在PubMed图书馆中发现了851项研究，在Scopus中发现了1961项研究（共2812项研究）。结果：经过初步评估，23种出版物最终被包括在分析中。总研究人群包括6,093,497名参与者。关于流感疫苗，疫苗接种率从2.5%的低接种率到97%的极高接种率，而肺炎球菌疫苗接种覆盖率分别为20%至84.6%。大多数研究证明了疫苗接种对生存和住院的有益影响。结论：本系统综述研究表明，心力衰竭患者的疫苗接种覆盖率多种多样。
