PDF(Pubmed)
Abstract：
The treatment of head and neck cancers (HNCs) encompasses a complex paradigm involving a combination of surgery, radiotherapy, and systemic treatment. Locoregional recurrence is a common cause of treatment failure, and few patients are suitable for salvage surgery. Reirradiation with conventional radiation techniques is challenging due to normal tissue tolerance limits and the risk of significant toxicities. Stereotactic body radiotherapy (SBRT) has emerged as a highly conformal modality that offers the potential for cure while limiting the dose to surrounding tissue. There is also growing research that shows that those with oligometastatic disease can benefit from curative intent local ablative therapies such as SBRT. This review will look at published evidence regarding the use of SBRT in locoregional recurrent and oligometastatic HNCs.
摘要：
头颈癌（HNC）的治疗包括一个复杂的范例，涉及手术的组合，放射治疗,和系统治疗。局部复发是治疗失败的常见原因，很少有患者适合进行抢救手术。由于正常组织耐受极限和显著毒性的风险,用常规辐射技术进行再辐射是具有挑战性的。立体定向身体放射治疗（SBRT）已经成为一种高度适形的方式，它提供了治愈的潜力，同时将剂量限制在周围组织中。也有越来越多的研究表明，患有寡转移疾病的人可以从治愈性局部消融疗法（如SBRT）中受益。这篇综述将研究有关SBRT在局部复发性和寡转移性HNC中使用的已发表证据。
