PDF(Pubmed)
Abstract：
The administration of GnRH and its agonists benefits various aspects of bovine reproductive programs, encompassing physiological stages such as estrous synchronization, post-insemination, pregnancy, and the postpartum period. The positive impact of GnRH administration in overcoming challenges like repeat breeder cows, early embryonic loss prevention, and the management of cystic ovarian disease (COD) is thoroughly surveyed. Furthermore, this review focuses on the significance of GnRH administration during the postpartum period, its role in ovulation induction, and how it enhances the productivity of embryo transfer (ET) programs. An emerging feature of this field is introduced, focusing on nano-drug delivery systems for GnRH agonists, and the potential benefits that may arise from such advancements are highlighted. While this review offers valuable insights into various applications of GnRH in bovine reproduction, it emphasizes the crucial need for further research and development in this field to advance reproductive efficiency and health management in dairy cattle.
摘要：
GnRH及其激动剂的给药有利于牛生殖计划的各个方面，包括生理阶段，如动情同步，授精后,怀孕,和产后。GnRH管理在克服重复饲养牛等挑战方面的积极影响，早期胚胎丢失预防，并对囊性卵巢疾病（COD）的管理进行了全面调查。此外，这篇综述集中在产后期间GnRH管理的意义，它在诱导排卵中的作用，以及它如何提高胚胎移植（ET）计划的生产率。介绍了该领域的一个新兴特征，专注于GnRH激动剂的纳米药物递送系统，并强调了这种进步可能带来的潜在好处。虽然这篇综述为GnRH在牛繁殖中的各种应用提供了有价值的见解，它强调迫切需要在这一领域进行进一步的研究和开发，以提高奶牛的生殖效率和健康管理。
