关键词: Arterial embolism Occult cancer Screening Venous thromboembolism

来  源:   DOI:10.1186/s12959-024-00622-7   PDF(Pubmed)

Abstract:
The link between venous thromboembolism (VTE) and cancer is well known. VTE could be the initial sign of an occult malignancy. There are more diagnoses of cancer after an unprovoked VTE compared to a provoked VTE, with a reported prevalence between 4.5% and 5.6% over 12 months, within the first 6 months of VTE diagnosis. There are no recommended guidelines and scores yet adopted in clinical practice, but many studies support occult cancer screening in unprovoked VTE patients. We report the case of a patient with a history of unprovoked pulmonary embolism (PE) diagnosed with bronchopulmonary neoplasm in an advanced stage one year after the thromboembolic event. When the cancer was first diagnosed, the patient\'s condition was already serious, being too late for the adoption of measures meant to decrease the risk of mortality and increase the duration of survival. We wanted to emphasize the importance of occult cancer screening in patients with unprovoked VTE and the fact that early cancer diagnosis reduces the risk of cancer progression, decreasing mortality and morbidity related to it.
摘要:
静脉血栓栓塞(VTE)与癌症之间的联系是众所周知的。VTE可能是隐匿性恶性肿瘤的最初征兆。与引起的VTE相比,无缘无故的VTE后有更多的癌症诊断,报告的12个月患病率在4.5%至5.6%之间,在VTE诊断的前6个月内。在临床实践中尚无推荐的指南和评分。但许多研究支持对无端VTE患者进行隐匿性癌症筛查.我们报告了一例有无源性肺栓塞(PE)病史的患者,该患者在血栓栓塞事件发生一年后的晚期被诊断为支气管肺肿瘤。当癌症第一次被诊断出来时,病人的病情已经很严重,采取旨在降低死亡风险和延长生存时间的措施为时已晚。我们想强调隐匿性癌症筛查对无端VTE患者的重要性,以及早期癌症诊断降低癌症进展风险的事实。降低与之相关的死亡率和发病率。
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