PDF(Pubmed)
Abstract：
Eclampsia spectrum disorders are a set of serious complications of pregnancy that commonly present after 20 weeks of gestation. There is an association between molar pregnancy, a gestational trophoblastic disease resulting from abnormal fertilisation and gametogenesis, and eclampsia spectrum disorders which can result in manifestation of pre-eclamptic symptomatology earlier than 20 weeks of gestation. We report a case of a gravida 1 para 0 in her mid 20s at 16-weeks gestation presenting with partial hydatidiform mole who developed eclampsia, haemolysis, elevated liver enzymes and low platelets syndrome and posterior reversible encephalopathy syndrome. Ultrasound findings were consistent with molar pregnancy and pathology confirmed partial molar pregnancy with triploid 69, XYY karyotype. This case highlights the early onset potential of eclampsia spectrum disorders in molar pregnancies while suggesting screening such patients for hypertensive disorders.
摘要：
子痫谱系障碍是一组严重的妊娠并发症，通常在妊娠20周后出现。磨牙怀孕之间有联系，一种由受精和配子生成异常引起的妊娠滋养细胞疾病，和子痫谱系障碍，可导致先兆子痫症状的表现早于妊娠20周。我们报告了一例妊娠16周时20多岁时妊娠1para0的病例，出现部分葡萄胎，患有子痫，溶血,肝酶升高和低血小板综合征和后部可逆性脑病综合征。超声检查结果与磨牙妊娠一致，病理证实磨牙部分妊娠具有三倍体69，XYY核型。该病例突出了磨牙妊娠中子痫谱系障碍的早发性潜力，同时建议对此类患者进行高血压疾病筛查。
