Abstract：
BACKGROUND: Individuals with a history of Adverse Childhood Experiences (ACEs) are at risk of subsequent cannabis use. However, at present no existing systematic review explores ACEs as they relate to cannabis use.
OBJECTIVE: The aim of this systematic review paper is to examine how adverse childhood experiences (ACEs) impact rates, patterns, and the nature of cannabis use in adulthood.
METHODS: Guided by the PRISMA statement, this systematic review focuses on longitudinal studies that report cannabis use in adulthood. Databases searched include PubMed and Embase.
RESULTS: Ultimately, 28 manuscripts were selected for inclusion, ranging in scope from smaller community-focused studies to nationally representative longitudinal surveys; 22 of 28 studies occurred in the United States, with sample size ranging from 303 to 15,960 participants. Instruments used to assess ACEs and cannabis use varied considerably across studies, leading to loss of consistency. Nevertheless, presence of ACEs-childhood sexual abuse in particular-was consistently associated with cannabis use later in life. Frequency and severity of ACEs was found to exert an additive cumulative effect on severity of cannabis use.
CONCLUSIONS: This systematic review lays the foundation of the current state of the science regarding ACEs and cannabis use, which can provide further insight into a better understanding of this relationship and provide potential intervention opportunities.
OBJECTIVE: The aim of this systematic review paper is to examine how adverse childhood experiences (ACEs) impact rates, patterns, and the nature of cannabis use in adulthood.
METHODS: Guided by the PRISMA statement, this systematic review focuses on longitudinal studies that report cannabis use in adulthood. Databases searched include PubMed and Embase.
RESULTS: Ultimately, 28 manuscripts were selected for inclusion, ranging in scope from smaller community-focused studies to nationally representative longitudinal surveys; 22 of 28 studies occurred in the United States, with sample size ranging from 303 to 15,960 participants. Instruments used to assess ACEs and cannabis use varied considerably across studies, leading to loss of consistency. Nevertheless, presence of ACEs-childhood sexual abuse in particular-was consistently associated with cannabis use later in life. Frequency and severity of ACEs was found to exert an additive cumulative effect on severity of cannabis use.
CONCLUSIONS: This systematic review lays the foundation of the current state of the science regarding ACEs and cannabis use, which can provide further insight into a better understanding of this relationship and provide potential intervention opportunities.
摘要：
背景：有不良童年经历（ACE）病史的个体有随后使用大麻的风险。然而,目前尚无现有的系统评价探讨与大麻使用相关的ACE.
目的：这篇系统综述论文的目的是研究不良儿童经历（ACE）如何影响发病率，模式,以及成年后使用大麻的性质。
方法：在PRISMA声明的指导下，本系统综述集中于报道成年期使用大麻的纵向研究.搜索的数据库包括PubMed和Embase。
结果：最终，28份手稿被选中列入，范围从较小的以社区为重点的研究到具有全国代表性的纵向调查；28项研究中有22项发生在美国，样本量为303至15,960名参与者。用于评估ACEs和大麻使用的仪器在研究中差异很大，导致一致性的丧失。然而，ACEs的存在-特别是儿童时期的性虐待-始终与以后生活中的大麻使用相关。发现ACEs的频率和严重程度对大麻使用的严重程度产生累加累积影响。
结论：本系统综述奠定了关于ACE和大麻使用的科学现状的基础，这可以进一步深入了解这种关系，并提供潜在的干预机会。
目的：这篇系统综述论文的目的是研究不良儿童经历（ACE）如何影响发病率，模式,以及成年后使用大麻的性质。
方法：在PRISMA声明的指导下，本系统综述集中于报道成年期使用大麻的纵向研究.搜索的数据库包括PubMed和Embase。
结果：最终，28份手稿被选中列入，范围从较小的以社区为重点的研究到具有全国代表性的纵向调查；28项研究中有22项发生在美国，样本量为303至15,960名参与者。用于评估ACEs和大麻使用的仪器在研究中差异很大，导致一致性的丧失。然而，ACEs的存在-特别是儿童时期的性虐待-始终与以后生活中的大麻使用相关。发现ACEs的频率和严重程度对大麻使用的严重程度产生累加累积影响。
结论：本系统综述奠定了关于ACE和大麻使用的科学现状的基础，这可以进一步深入了解这种关系，并提供潜在的干预机会。
