PDF(Pubmed)
Abstract：
BACKGROUND: Kartagener syndrome is rare, with an incidence of 1 in 32,000 live births. It consists of a triad of bronchiectasis, situs inversus, and sinusitis. Normally, the middle lobe is part of the right lung, but due to situs inversus, the middle lobe is part of the left lung, making it prone to bronchiectasis and infections.
METHODS: We present a unique case of a 16-year-old adolescent with a known history of Kartagener syndrome who presented with recurrent chest infections and hemoptysis refractory to conservative management. He was diagnosed with bronchiectasis of the left middle lobe through a computed tomography (CT) scan and subsequently underwent a posterolateral thoracotomy and left middle lobectomy. This is a rare finding with limited literature available on such cases, to the best of our knowledge.
CONCLUSIONS: Conservative treatment is usually the first line of approach. However, in cases of recurrent chest infections and hemoptysis, surgical management is considered to prevent the infection from spreading to the healthy lung and to avoid life-threatening complications when medical therapy fails. Surgical intervention, while more invasive, can provide a definitive solution and improve the patient\'s quality of life.
CONCLUSIONS: Early diagnosis of Kartagener syndrome is crucial for determining the appropriate management course. In patients presenting with recurrent hemoptysis and chest infections, surgical resection is an effective treatment approach to prevent complications and enhance long-term outcomes.
METHODS: We present a unique case of a 16-year-old adolescent with a known history of Kartagener syndrome who presented with recurrent chest infections and hemoptysis refractory to conservative management. He was diagnosed with bronchiectasis of the left middle lobe through a computed tomography (CT) scan and subsequently underwent a posterolateral thoracotomy and left middle lobectomy. This is a rare finding with limited literature available on such cases, to the best of our knowledge.
CONCLUSIONS: Conservative treatment is usually the first line of approach. However, in cases of recurrent chest infections and hemoptysis, surgical management is considered to prevent the infection from spreading to the healthy lung and to avoid life-threatening complications when medical therapy fails. Surgical intervention, while more invasive, can provide a definitive solution and improve the patient\'s quality of life.
CONCLUSIONS: Early diagnosis of Kartagener syndrome is crucial for determining the appropriate management course. In patients presenting with recurrent hemoptysis and chest infections, surgical resection is an effective treatment approach to prevent complications and enhance long-term outcomes.
摘要：
背景：Kartagener综合征很少见，发病率为32,000名活产儿中的1名。它由支气管扩张的三合会组成，situsinversus,和鼻窦炎.通常,中叶是右肺的一部分,但是由于坐位倒置，中叶是左肺的一部分,使其容易发生支气管扩张和感染。
方法：我们介绍了一例16岁青少年的独特病例，已知有Kartagener综合征病史，该患者反复出现胸部感染和咯血，保守治疗难以治疗。通过计算机断层扫描（CT）扫描，他被诊断为左中叶支气管扩张，随后进行了后外侧开胸手术和左中叶切除术。这是一个罕见的发现，关于这种情况的文献有限，据我们所知.
结论：保守治疗通常是一线治疗方法。然而,在复发性胸部感染和咯血的情况下，手术治疗被认为可以防止感染扩散到健康的肺部，并在药物治疗失败时避免危及生命的并发症。手术干预,虽然更具侵入性，可以提供明确的解决方案，提高患者的生活质量。
结论：Kartagener综合征的早期诊断对于确定适当的治疗方案至关重要。在反复咯血和胸部感染的患者中，手术切除是预防并发症和提高远期疗效的有效治疗方法.
方法：我们介绍了一例16岁青少年的独特病例，已知有Kartagener综合征病史，该患者反复出现胸部感染和咯血，保守治疗难以治疗。通过计算机断层扫描（CT）扫描，他被诊断为左中叶支气管扩张，随后进行了后外侧开胸手术和左中叶切除术。这是一个罕见的发现，关于这种情况的文献有限，据我们所知.
结论：保守治疗通常是一线治疗方法。然而,在复发性胸部感染和咯血的情况下，手术治疗被认为可以防止感染扩散到健康的肺部，并在药物治疗失败时避免危及生命的并发症。手术干预,虽然更具侵入性，可以提供明确的解决方案，提高患者的生活质量。
结论：Kartagener综合征的早期诊断对于确定适当的治疗方案至关重要。在反复咯血和胸部感染的患者中，手术切除是预防并发症和提高远期疗效的有效治疗方法.
