PDF(Pubmed)
Abstract：
Butyl butyrate is a short-chain fatty acid ester (C8) with a fruity aroma. It has broad prospects in the fields of foods, cosmetics and biofuels. At present, butyl butyrate is produced by chemical synthesis in the industry, but it is highly dependent on petroleum-based products. The growing concerns regarding the future scarcity of fossil fuels have been strongly promoted the transition from traditional fossil fuels and products to renewable bioenergy and biochemicals. Therefore, it is necessary to develop a green biochemical technology to replace traditional petroleum-based materials. In recent years, microorganisms such as Escherichia coli and Clostridium have been engineered to serve as cell factories for the sustainable one-pot production of short-chain fatty acid esters, including butyl butyrate. This opinion highlights the recent development in the use of lipases and alcohol acyltransferases (AATs) for butyl butyrate production in microbial fermentation, as well as future perspectives.
摘要：
丁酸丁酯是一种短链脂肪酸酯（C8），具有果香。它在食品领域具有广阔的前景，化妆品和生物燃料。目前,丁酸丁酯是在工业上通过化学合成生产的，但它高度依赖石油基产品。对未来化石燃料稀缺性的日益关注已经有力地促进了从传统化石燃料和产品向可再生生物能源和生物化学品的过渡。因此,有必要开发绿色生化技术来替代传统的石油基材料。近年来,大肠杆菌和梭状芽孢杆菌等微生物已被设计为可持续一锅生产短链脂肪酸酯的细胞工厂，包括丁酸丁酯.这一观点强调了在微生物发酵中使用脂肪酶和醇酰基转移酶（AATs）生产丁酸丁酯的最新发展，以及未来的前景。
