PDF(Pubmed)
Abstract：
UNASSIGNED: Today, antibiotics are widely used for treatment and feed additives to enhance livestock growth. Antibiotic residues may be found in food of animal origin for various reasons, including ignoring the withdrawal period after treatment, overuse for animals, and contamination of feed with treated animals in animal products. Among animal products, dairy products have a special place in the human diet, and antibiotic residues in them have caused a great deal of concern among consumers.
UNASSIGNED: This systematic review and meta-analysis aimed to evaluate and compare studies conducted in Iran on antibiotic residues in dairy products during 2000-2022.
UNASSIGNED: In this review, 52 eligible studies were collected by searching the Scientific Information Database (SID), Magiran, Google Scholar, Science-Direct, Scopus, and PubMed using the English or Persian keywords such as an antibiotic or antimicrobial residue, Beta-lactam residue, Tetracycline residue, Sulfonamide residue, Chloramphenicol residue, Aminoglycosides residue, Macrolide residue, Quinolones residue, Milk, Raw milk, Pasteurized milk, UHT milk, Powder milk, Cheese, Yogurt, Butter, Cream, Doogh, Kashk, Ice cream, and Iran.
UNASSIGNED: According to the reviewed studies, the total prevalence of antibiotic residues in dairy products was 29% (95% CI: 15-43%). Among the seven evaluated antibiotic groups, most studies have been conducted on tetracycline, beta-lactam, and sulfonamide groups, with 16, 10, and 7 respectively, and the highest level of contamination with 663 ± 1540 μg/l is related to tetracycline. Most studies on antibiotic dairy product residues in Iran with 12, 11, and 8 studies are associated with East Azarbaijan province, then Tehran and Khorasan Razavi respectively, and no study has been conducted in 11 provinces of the country. According to the studies, Gilan, Qazvin and Razavi Khorasan provinces had the highest amount of antibiotic residue in milk with an average value of 56.415 ± 33.354, 45.955 ± 4.179 and 45.928 ± 33.027, respectively. Most of the methods used in the studies to measure antibiotic residues in milk were the Copan test kit and the HPLC method, which were used in 19 and 14 studies, respectively.
UNASSIGNED: Studies have shown that the prevalence of antibiotic residue in dairy products in Iran is high, so applying an effective strategy and developing the necessary standards in this field to control milk quality is a public health necessity. The findings of this study show that further evaluation of fermented dairy products, especially non-fermented ones such as butter and cream, is needed to prevent adverse health reactions.
UNASSIGNED: This systematic review and meta-analysis aimed to evaluate and compare studies conducted in Iran on antibiotic residues in dairy products during 2000-2022.
UNASSIGNED: In this review, 52 eligible studies were collected by searching the Scientific Information Database (SID), Magiran, Google Scholar, Science-Direct, Scopus, and PubMed using the English or Persian keywords such as an antibiotic or antimicrobial residue, Beta-lactam residue, Tetracycline residue, Sulfonamide residue, Chloramphenicol residue, Aminoglycosides residue, Macrolide residue, Quinolones residue, Milk, Raw milk, Pasteurized milk, UHT milk, Powder milk, Cheese, Yogurt, Butter, Cream, Doogh, Kashk, Ice cream, and Iran.
UNASSIGNED: According to the reviewed studies, the total prevalence of antibiotic residues in dairy products was 29% (95% CI: 15-43%). Among the seven evaluated antibiotic groups, most studies have been conducted on tetracycline, beta-lactam, and sulfonamide groups, with 16, 10, and 7 respectively, and the highest level of contamination with 663 ± 1540 μg/l is related to tetracycline. Most studies on antibiotic dairy product residues in Iran with 12, 11, and 8 studies are associated with East Azarbaijan province, then Tehran and Khorasan Razavi respectively, and no study has been conducted in 11 provinces of the country. According to the studies, Gilan, Qazvin and Razavi Khorasan provinces had the highest amount of antibiotic residue in milk with an average value of 56.415 ± 33.354, 45.955 ± 4.179 and 45.928 ± 33.027, respectively. Most of the methods used in the studies to measure antibiotic residues in milk were the Copan test kit and the HPLC method, which were used in 19 and 14 studies, respectively.
UNASSIGNED: Studies have shown that the prevalence of antibiotic residue in dairy products in Iran is high, so applying an effective strategy and developing the necessary standards in this field to control milk quality is a public health necessity. The findings of this study show that further evaluation of fermented dairy products, especially non-fermented ones such as butter and cream, is needed to prevent adverse health reactions.
摘要：
■今天,抗生素被广泛用于治疗和饲料添加剂，以促进牲畜生长。由于各种原因，动物源性食品中可能会发现抗生素残留。包括忽略治疗后的停药期，过度使用动物，以及动物产品中处理过的动物对饲料的污染。在动物产品中，乳制品在人类饮食中占有特殊的地位,其中的抗生素残留引起了消费者的极大关注。
■这项系统综述和荟萃分析旨在评估和比较在伊朗进行的关于2000-2022年间乳制品中抗生素残留的研究。
■在这篇评论中，通过搜索科学信息数据库（SID）收集了52项符合条件的研究，马吉兰,谷歌学者，科学直接，Scopus,和PubMed使用英语或波斯语关键字，如抗生素或抗菌残留物，β-内酰胺残留物，四环素残留,磺酰胺残留物,氯霉素残留物，氨基糖苷残基，大环内酯残留物,喹诺酮类药物残留,牛奶,生牛奶,巴氏杀菌牛奶,UHT牛奶，奶粉,奶酪,酸奶,黄油,奶油,Doogh,卡什,冰淇淋,和伊朗。
■根据审查的研究，乳制品中抗生素残留的总患病率为29%(95%CI:15-43%).在七个评估的抗生素组中，大多数研究都是在四环素上进行的，β-内酰胺，和磺酰胺基团，分别为16、10和7，663±1540μg/l的最高污染水平与四环素有关。大多数关于伊朗抗生素乳制品残留的研究有12、11和8项研究与东阿塞拜疆省有关，然后分别是德黑兰和霍拉桑·拉扎维，没有在全国11个省进行过研究。根据研究,吉兰,Qazvin和RazaviKhorasan省的牛奶中抗生素残留量最高，平均值分别为56.415±33.354、45.955±4.179和45.928±33.027。研究中用于测量牛奶中抗生素残留的大多数方法是Copan检测试剂盒和HPLC法，在19和14项研究中使用，分别。
■研究表明，伊朗乳制品中抗生素残留的患病率很高，因此，在该领域应用有效的策略并制定必要的标准来控制牛奶质量是公共卫生的必要条件。这项研究的结果表明，进一步评价发酵乳制品，尤其是非发酵的，如黄油和奶油，是预防不良健康反应所必需的。
■这项系统综述和荟萃分析旨在评估和比较在伊朗进行的关于2000-2022年间乳制品中抗生素残留的研究。
■在这篇评论中，通过搜索科学信息数据库（SID）收集了52项符合条件的研究，马吉兰,谷歌学者，科学直接，Scopus,和PubMed使用英语或波斯语关键字，如抗生素或抗菌残留物，β-内酰胺残留物，四环素残留,磺酰胺残留物,氯霉素残留物，氨基糖苷残基，大环内酯残留物,喹诺酮类药物残留,牛奶,生牛奶,巴氏杀菌牛奶,UHT牛奶，奶粉,奶酪,酸奶,黄油,奶油,Doogh,卡什,冰淇淋,和伊朗。
■根据审查的研究，乳制品中抗生素残留的总患病率为29%(95%CI:15-43%).在七个评估的抗生素组中，大多数研究都是在四环素上进行的，β-内酰胺，和磺酰胺基团，分别为16、10和7，663±1540μg/l的最高污染水平与四环素有关。大多数关于伊朗抗生素乳制品残留的研究有12、11和8项研究与东阿塞拜疆省有关，然后分别是德黑兰和霍拉桑·拉扎维，没有在全国11个省进行过研究。根据研究,吉兰,Qazvin和RazaviKhorasan省的牛奶中抗生素残留量最高，平均值分别为56.415±33.354、45.955±4.179和45.928±33.027。研究中用于测量牛奶中抗生素残留的大多数方法是Copan检测试剂盒和HPLC法，在19和14项研究中使用，分别。
■研究表明，伊朗乳制品中抗生素残留的患病率很高，因此，在该领域应用有效的策略并制定必要的标准来控制牛奶质量是公共卫生的必要条件。这项研究的结果表明，进一步评价发酵乳制品，尤其是非发酵的，如黄油和奶油，是预防不良健康反应所必需的。
