PDF(Pubmed)
Abstract：
UNASSIGNED: To objectively measure visual function amongst Primary Open Angle Glaucoma (POAG) patients and compare these with age and sex-matched controls by describing the characteristics of visual function in relation to the severity of POAG.
UNASSIGNED: A case-control study was carried out among 106 POAG patients and an equal number of age-sex matched controls attending Asokoro District Hospital, Abuja, and Eye Foundation Hospital Abuja from Nov 2012 to April 2013. The objective measures of visual function assessed include visual acuity (VA), contrast sensitivity (CS), colour vision (CV), and visual fields (MD) in the better eye (BE)].
UNASSIGNED: All measures of visual function were found to be reduced comparing cases to controls and this was statistically significant. VABE (0.39±0.73; 0.0017±0.02p<0.001); MDBE (-8.02±6.80; 0.17±0.3P<0.001); CSBE (1.46±0.59; 1.90±0.16p<0.001): Colour vision defects (54.7%; 6.6% p<0.001). In comparing mild; moderate; severe glaucoma: VABE (0.0053±0.03; 0.057±0.08; 0.766±0.90 p<0.001); MDBE (-3.46±1.93;-8.17±3.55;-16.43±6.01p <0.001); CSBE (1.88±0.26; 1.69± 0.37; 1.11±0.59 p<0.001): Color vision defects (20.6%; 31.6%; 86.9%) respectively (BE: Better Eye). While looking at the two independent groups above, mild and moderate were not statistically significant except for the visual field, but comparing mild with severe and moderate with severe, they had a statistically significant relationship across all the visual functions tested. In comparing controls with mild, color vision and visual field had a statistically significant difference. Comparing the groups with mild and moderate glaucoma, only visual fields as a visual function were statistically significant. Whereas comparing both groups with the severe group independently, they had statistically significant in all the visual functions tested.
UNASSIGNED: In conclusion, visual function was reduced in glaucoma patients as compared to controls. Visual acuity, contrast sensitivity and colour vision differed significantly in comparing mild with severe and moderate with severe. Color vision differed significantly in comparing mild to controls.
UNASSIGNED: A case-control study was carried out among 106 POAG patients and an equal number of age-sex matched controls attending Asokoro District Hospital, Abuja, and Eye Foundation Hospital Abuja from Nov 2012 to April 2013. The objective measures of visual function assessed include visual acuity (VA), contrast sensitivity (CS), colour vision (CV), and visual fields (MD) in the better eye (BE)].
UNASSIGNED: All measures of visual function were found to be reduced comparing cases to controls and this was statistically significant. VABE (0.39±0.73; 0.0017±0.02p<0.001); MDBE (-8.02±6.80; 0.17±0.3P<0.001); CSBE (1.46±0.59; 1.90±0.16p<0.001): Colour vision defects (54.7%; 6.6% p<0.001). In comparing mild; moderate; severe glaucoma: VABE (0.0053±0.03; 0.057±0.08; 0.766±0.90 p<0.001); MDBE (-3.46±1.93;-8.17±3.55;-16.43±6.01p <0.001); CSBE (1.88±0.26; 1.69± 0.37; 1.11±0.59 p<0.001): Color vision defects (20.6%; 31.6%; 86.9%) respectively (BE: Better Eye). While looking at the two independent groups above, mild and moderate were not statistically significant except for the visual field, but comparing mild with severe and moderate with severe, they had a statistically significant relationship across all the visual functions tested. In comparing controls with mild, color vision and visual field had a statistically significant difference. Comparing the groups with mild and moderate glaucoma, only visual fields as a visual function were statistically significant. Whereas comparing both groups with the severe group independently, they had statistically significant in all the visual functions tested.
UNASSIGNED: In conclusion, visual function was reduced in glaucoma patients as compared to controls. Visual acuity, contrast sensitivity and colour vision differed significantly in comparing mild with severe and moderate with severe. Color vision differed significantly in comparing mild to controls.
摘要：
■为了客观地测量原发性开角型青光眼（POAG）患者的视觉功能，并通过描述与POAG严重程度相关的视觉功能特征将其与年龄和性别匹配的对照进行比较。
对106名POAG患者和在Asokoro区医院就诊的同等数量的年龄性别匹配对照进行了病例对照研究，阿布贾,和2012年11月至2013年4月的阿布贾眼科基金会医院。评估视觉功能的客观指标包括视敏度（VA），对比敏感度（CS），彩色视觉(CV),和视野（MD）在更好的眼睛（BE）]。
■与对照组相比，发现所有视觉功能指标均降低，具有统计学意义。VABE(0.39±0.73;0.0017±0.02p<0.001);MDBE(-8.02±6.80;0.17±0.3P<0.001);CSBE(1.46±0.59;1.90±0.16p<0.001):色觉缺陷(54.7%;6.6%p<0.001)。比较轻度；中度；重度青光眼：VABE（0.0053±0.03；0.057±0.08；0.766±0.90p<0.001）；MDBE（-3.46±1.93；-8.17±3.55；-16.43±6.01p<0.001）；CSBE（1.88±0.26；1.69±0.37；1.11±0.59p<0.001）：色觉缺陷（分别为20.6％；31.6％；在观察上面两个独立的群体时，轻度和中度除视野外无统计学意义，但是比较轻度和重度，中度和重度，在所有测试的视觉功能中，它们具有统计学上显著的关系。在比较对照组和轻度，色觉和视野差异有统计学意义。比较轻度和中度青光眼组，只有作为视觉功能的视野有统计学意义.而两组与重症组独立比较，他们在所有测试的视觉功能中具有统计学意义。
■总而言之，与对照组相比,青光眼患者的视觉功能降低.视敏度,与轻度和重度以及中度和重度相比，对比敏感度和色觉差异显着。与轻度对照相比，色觉明显不同。
对106名POAG患者和在Asokoro区医院就诊的同等数量的年龄性别匹配对照进行了病例对照研究，阿布贾,和2012年11月至2013年4月的阿布贾眼科基金会医院。评估视觉功能的客观指标包括视敏度（VA），对比敏感度（CS），彩色视觉(CV),和视野（MD）在更好的眼睛（BE）]。
■与对照组相比，发现所有视觉功能指标均降低，具有统计学意义。VABE(0.39±0.73;0.0017±0.02p<0.001);MDBE(-8.02±6.80;0.17±0.3P<0.001);CSBE(1.46±0.59;1.90±0.16p<0.001):色觉缺陷(54.7%;6.6%p<0.001)。比较轻度；中度；重度青光眼：VABE（0.0053±0.03；0.057±0.08；0.766±0.90p<0.001）；MDBE（-3.46±1.93；-8.17±3.55；-16.43±6.01p<0.001）；CSBE（1.88±0.26；1.69±0.37；1.11±0.59p<0.001）：色觉缺陷（分别为20.6％；31.6％；在观察上面两个独立的群体时，轻度和中度除视野外无统计学意义，但是比较轻度和重度，中度和重度，在所有测试的视觉功能中，它们具有统计学上显著的关系。在比较对照组和轻度，色觉和视野差异有统计学意义。比较轻度和中度青光眼组，只有作为视觉功能的视野有统计学意义.而两组与重症组独立比较，他们在所有测试的视觉功能中具有统计学意义。
■总而言之，与对照组相比,青光眼患者的视觉功能降低.视敏度,与轻度和重度以及中度和重度相比，对比敏感度和色觉差异显着。与轻度对照相比，色觉明显不同。
