Abstract：
Histoplasmosis is a systemic infection caused by an endemic dimorphic fungus, Histoplasma capsulatum. Though prevalent in the eastern United States of America, near the Ohio and Mississippi River Valleys, the evidence underlying the global prevalence of histoplasmosis, especially in immunocompromised populations, is underappreciated. This article highlights the global epidemiology, risk factors, microbiology and pathophysiological characteristics, pulmonary and extrapulmonary manifestations, prevention measures, radiographic patterns, diagnostic techniques, and antifungal treatment approaches for Histoplasma capsulatum.
摘要：
组织胞浆菌病是由地方性二态真菌引起的全身性感染，荚膜组织胞浆。尽管在美国东部很普遍，在俄亥俄州和密西西比河山谷附近，组织胞浆菌病全球流行的证据，尤其是在免疫功能低下的人群中，被低估了。本文重点介绍了全球流行病学，危险因素，微生物学和病理生理特征，肺和肺外表现，预防措施,射线照相模式，诊断技术,和包膜组织胞浆的抗真菌治疗方法。
