PDF(Pubmed)
Abstract：
Cochlear implantation is an effective intervention to restore useful aspects of hearing function in adults with severe-to-profound hearing loss. Tinnitus, the perception of sound in the absence of an external source, is common in people with severe-to-profound hearing loss. Existing evidence suggests cochlear implantation may be effective in reducing the negative impact of tinnitus in this population. However, this is contradicted by data suggesting that up to half of cochlear implant recipients experience tinnitus, and that some of these patients who did not have tinnitus before cochlear implantation experience it after surgery or cochlear implant activation. Most evidence on the effects of cochlear implantation on tinnitus comes from secondary data in cochlear implant studies primarily concerned with hearing-related outcomes. Hence, the quality of the evidence for effects on tinnitus is low and not suitable to inform clinical recommendations or decision-making. This study will systematically collect data on tinnitus and tinnitus-related outcomes from patients at multiple points during the cochlear implant pathway to characterise changes in tinnitus. This will improve our understanding of the effects of cochlear implantation for tinnitus in adults with severe to profound hearing loss and inform the design of clinical trials of cochlear implantation for tinnitus.
摘要：
人工耳蜗植入是一种有效的干预措施，可以恢复重度至重度听力损失的成年人的听力功能。耳鸣,在没有外部来源的情况下对声音的感知，在严重到严重听力损失的人中很常见。现有证据表明，人工耳蜗植入可能有效减少耳鸣对该人群的负面影响。然而,这与数据相矛盾，数据表明，多达一半的人工耳蜗接受者会出现耳鸣，并且其中一些在人工耳蜗植入之前没有耳鸣的患者在手术或人工耳蜗植入激活后经历耳鸣。关于人工耳蜗植入对耳鸣影响的大多数证据来自人工耳蜗植入研究的次要数据，主要涉及听力相关结果。因此，耳鸣效应的证据质量较低,不适合为临床建议或决策提供依据.这项研究将系统地收集有关耳鸣和耳鸣相关结果的数据，这些数据来自耳蜗植入途径中多个点的患者，以表征耳鸣的变化。这将提高我们对严重至严重听力损失的成人人工耳蜗植入耳鸣的影响的理解，并为人工耳蜗植入耳鸣的临床试验的设计提供信息。
