PDF(Pubmed)
Abstract：
UNASSIGNED: Postoperative complications may occur after major lung surgery for non-small cell lung cancer (NSCLC), with a high rate of morbidity and mortality. The main objective of this study was to assess the relevance of preoperative Leicester Cough Questionnaire (LCQ) to predict postoperative complications after major lung resection for any indication.
UNASSIGNED: This was a retrospective cohort study conducted in the Thoracic Surgery Department of Rouen University Hospital from November 21st, 2022, to June 2nd, 2023. Patients aged ≥18 years who underwent major lung resection for any indications and filled an LCQ self-questionnaire were included.
UNASSIGNED: Seventy-one patients were eligible for our study. One patient was lost to follow-up upon hospital discharge. Nineteen (27.1%) postoperative complications of grade ≥2 according to the Clavien-Dindo classification were observed. The mean LCQ total score was 18.11±2.56. The area under the receiver operating characteristic (ROC) curve for the LCQ result to predict postoperative complications of grade ≥2 within 30 days following the surgical intervention was 0.60 [95% confidence interval (CI): 0.45, 0.75].
UNASSIGNED: This study failed to demonstrate the relevance of a preoperative LCQ to predict postoperative complications after major lung surgery. However, the statistical precision of this study was insufficient to show a moderate predictive performance. Further studies conducted in larger populations are needed.
UNASSIGNED: This was a retrospective cohort study conducted in the Thoracic Surgery Department of Rouen University Hospital from November 21st, 2022, to June 2nd, 2023. Patients aged ≥18 years who underwent major lung resection for any indications and filled an LCQ self-questionnaire were included.
UNASSIGNED: Seventy-one patients were eligible for our study. One patient was lost to follow-up upon hospital discharge. Nineteen (27.1%) postoperative complications of grade ≥2 according to the Clavien-Dindo classification were observed. The mean LCQ total score was 18.11±2.56. The area under the receiver operating characteristic (ROC) curve for the LCQ result to predict postoperative complications of grade ≥2 within 30 days following the surgical intervention was 0.60 [95% confidence interval (CI): 0.45, 0.75].
UNASSIGNED: This study failed to demonstrate the relevance of a preoperative LCQ to predict postoperative complications after major lung surgery. However, the statistical precision of this study was insufficient to show a moderate predictive performance. Further studies conducted in larger populations are needed.
摘要：
■非小细胞肺癌（NSCLC）的大型肺部手术后可能会发生术后并发症，具有很高的发病率和死亡率。这项研究的主要目的是评估术前莱斯特咳嗽问卷（LCQ）的相关性，以预测任何适应症的大肺切除术后的术后并发症。
这是一项11月21日在鲁昂大学医院胸外科进行的回顾性队列研究，2022年6月2日2023年。年龄≥18岁的患者因任何适应症而接受了大型肺切除术并填写了LCQ自我问卷。
■71名患者符合我们的研究条件。一名患者出院后失去随访。根据Clavien-Dindo分类，观察到19（27.1％）级≥2级的术后并发症。平均LCQ总分为18.11±2.56。LCQ结果预测手术干预后30天内≥2级术后并发症的受试者工作特征(ROC)曲线下面积为0.60[95%置信区间(CI):0.45,0.75]。
■本研究未能证明术前LCQ预测肺部大手术后并发症的相关性。然而,本研究的统计精度不足以显示中等预测性能.需要在更大的人群中进行进一步的研究。
这是一项11月21日在鲁昂大学医院胸外科进行的回顾性队列研究，2022年6月2日2023年。年龄≥18岁的患者因任何适应症而接受了大型肺切除术并填写了LCQ自我问卷。
■71名患者符合我们的研究条件。一名患者出院后失去随访。根据Clavien-Dindo分类，观察到19（27.1％）级≥2级的术后并发症。平均LCQ总分为18.11±2.56。LCQ结果预测手术干预后30天内≥2级术后并发症的受试者工作特征(ROC)曲线下面积为0.60[95%置信区间(CI):0.45,0.75]。
■本研究未能证明术前LCQ预测肺部大手术后并发症的相关性。然而,本研究的统计精度不足以显示中等预测性能.需要在更大的人群中进行进一步的研究。
