关键词: AIDS ATT CD4+ cells EPTB HAART HIV

来  源:   DOI:10.1007/s12070-024-04523-z   PDF(Pubmed)

Abstract:
HIV is a disease which reduces human resistant to fight. When our immunity becomes so weak that we are not able to fight even the common commensals of our body, this leads to what is called as an opportunistic infection. Tuberculosis is one of those most common type of opportunistic infection and in this pulmonary tuberculosis is more common. Extrapulmonary tuberculosis with HIV is the area of lesser research. In this study we tried to prove the Prevalence of extrapulmonary tuberculosis in AIDS patients and also the effect of combined HAART and ATT on prevalence of extrapulmonary tuberculosis and also its effect on Quality of life of the patient. This is a retrospective study conducted in a tertiary centre in the Department of Otorhinolaryngology & head and neck surgery from January 2020 to December 2020. A total of 80 patients were studied for 1 year. Confirmed cases of AIDS with extra pulmonary tuberculosis in head and neck region were studied, keeping all ethical issues in mind and after complete treatment of ATT along with HAART. After treatment, a significant number of patients got resolved with EPTB and gave positive response on their quality of life. Not only pulmonary tuberculosis, extrapulmonary tuberculosis with HIV is on the rise nowadays. Combined treatment of both can help in decreasing prevalence of extrapulmonary tuberculosis and improves quality of life.
摘要:
HIV是一种降低人类抵抗的疾病。当我们的免疫力变得如此虚弱,以至于我们甚至无法与身体的共同生活作斗争时,这导致所谓的机会性感染。结核病是最常见的机会性感染类型之一,在这种肺结核中更为常见。HIV肺外结核是研究较少的领域。在这项研究中,我们试图证明AIDS患者肺外结核的患病率,以及HAART和ATT联合对肺外结核患病率的影响以及对患者生活质量的影响。这是一项回顾性研究,于2020年1月至2020年12月在耳鼻咽喉头颈外科的三级中心进行。对80例患者进行了为期1年的研究。研究了头颈部艾滋病合并肺外结核的确诊病例,牢记所有道德问题,并在与HAART一起完成ATT治疗后。治疗后,相当数量的患者在EPTB治疗后得到缓解,并对其生活质量给予了积极的反应.不仅仅是肺结核,现在肺外结核感染艾滋病毒呈上升趋势。两者的联合治疗可以帮助降低肺外结核的患病率并改善生活质量。
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