PDF(Pubmed)
Abstract：
UNASSIGNED: This systematic review and meta-analysis of randomized controlled trials (RCTs) compare the impact of platysma muscle layer closure technique among patients undergoing thyroidectomy in terms of postoperative outcomes, specifically pain.
UNASSIGNED: Five electronic databases (PubMed, Scopus, Web of Science, Google Scholar, and Cochrane Central Register of Controlled Trials) were searched from inception until July 22, 2023. The Cochrane risk of bias tool 2 was employed for risk of bias (ROB) assessment. Data were pooled as mean difference (MD), standardized MD (SMD), or risk ratio (RR) based on data type (continuous or dichotomous) using RevMan software.
UNASSIGNED: This meta-analysis included four RCTs with a total of 426 patients. Three RCTs had a low risk of bias, while one had some concern regarding bias. The overall MD of the postoperative pain score favored the non-closure group over the closure group (MD = 0.63; 95% CI: [0.09, 1.18]; P = 0.02). However, no significant differences were observed between the two groups in terms of patient scar assessment scale (MD= -0.61; 95% CI: [-3.39, 2.17]; P = 0.67), observer scar assessment scale (SMD = 0.26; 95% CI: [-0.30, 0.81]; P = 0.37), length of the scar (MD = 0.27; 95% CI: [-0.12, 0.67]; P = 0.17), wound infection (RR = 0.63; 95% CI: [0.13, 3.16]; P = 0.57), and seroma or hematoma (RR = 3.00; 95% CI: [0.49, 18.55]; P = 0.24).
UNASSIGNED: Our findings suggest that the platysma muscle layer closure during thyroidectomy might lead to increased postoperative pain but does not significantly impact scar outcomes or postoperative complications.
UNASSIGNED: The online version contains supplementary material available at 10.1007/s12070-024-04503-3.
UNASSIGNED: Five electronic databases (PubMed, Scopus, Web of Science, Google Scholar, and Cochrane Central Register of Controlled Trials) were searched from inception until July 22, 2023. The Cochrane risk of bias tool 2 was employed for risk of bias (ROB) assessment. Data were pooled as mean difference (MD), standardized MD (SMD), or risk ratio (RR) based on data type (continuous or dichotomous) using RevMan software.
UNASSIGNED: This meta-analysis included four RCTs with a total of 426 patients. Three RCTs had a low risk of bias, while one had some concern regarding bias. The overall MD of the postoperative pain score favored the non-closure group over the closure group (MD = 0.63; 95% CI: [0.09, 1.18]; P = 0.02). However, no significant differences were observed between the two groups in terms of patient scar assessment scale (MD= -0.61; 95% CI: [-3.39, 2.17]; P = 0.67), observer scar assessment scale (SMD = 0.26; 95% CI: [-0.30, 0.81]; P = 0.37), length of the scar (MD = 0.27; 95% CI: [-0.12, 0.67]; P = 0.17), wound infection (RR = 0.63; 95% CI: [0.13, 3.16]; P = 0.57), and seroma or hematoma (RR = 3.00; 95% CI: [0.49, 18.55]; P = 0.24).
UNASSIGNED: Our findings suggest that the platysma muscle layer closure during thyroidectomy might lead to increased postoperative pain but does not significantly impact scar outcomes or postoperative complications.
UNASSIGNED: The online version contains supplementary material available at 10.1007/s12070-024-04503-3.
摘要：
■这项随机对照试验（RCTs）的系统评价和荟萃分析比较了颈肌肌层闭合技术对甲状腺切除术患者术后结局的影响，特别是疼痛。
■五个电子数据库(PubMed，Scopus,WebofScience,谷歌学者，和Cochrane中央受控试验登记册）从开始到2023年7月22日进行搜索。采用Cochrane偏倚风险工具2进行偏倚风险(ROB)评估。数据汇总为平均差(MD)，标准化MD(SMD)，或使用RevMan软件基于数据类型(连续或二分法)的风险比(RR)。
■这项荟萃分析包括4项RCT，共426例患者。三个随机对照试验的偏倚风险很低，而一个人对偏见有一些担忧。术后疼痛评分的总体MD优于非闭合组（MD=0.63；95％CI：[0.09，1.18]；P=0.02）。然而,两组患者瘢痕评估量表无显著差异(MD=-0.61;95%CI:[-3.39,2.17];P=0.67),观察者瘢痕评估量表(SMD=0.26；95%CI：[-0.30，0.81]；P=0.37)，瘢痕长度(MD=0.27;95%CI:[-0.12,0.67];P=0.17),伤口感染（RR=0.63；95%CI：[0.13，3.16]；P=0.57），血清或血肿（RR=3.00;95%CI：[0.49,18.55];P=0.24）。
■我们的研究结果表明，甲状腺切除术期间颈阔肌层闭合可能会导致术后疼痛增加，但不会显著影响瘢痕结局或术后并发症。
■在线版本包含补充材料，可在10.1007/s12070-024-04503-3获得。
■五个电子数据库(PubMed，Scopus,WebofScience,谷歌学者，和Cochrane中央受控试验登记册）从开始到2023年7月22日进行搜索。采用Cochrane偏倚风险工具2进行偏倚风险(ROB)评估。数据汇总为平均差(MD)，标准化MD(SMD)，或使用RevMan软件基于数据类型(连续或二分法)的风险比(RR)。
■这项荟萃分析包括4项RCT，共426例患者。三个随机对照试验的偏倚风险很低，而一个人对偏见有一些担忧。术后疼痛评分的总体MD优于非闭合组（MD=0.63；95％CI：[0.09，1.18]；P=0.02）。然而,两组患者瘢痕评估量表无显著差异(MD=-0.61;95%CI:[-3.39,2.17];P=0.67),观察者瘢痕评估量表(SMD=0.26；95%CI：[-0.30，0.81]；P=0.37)，瘢痕长度(MD=0.27;95%CI:[-0.12,0.67];P=0.17),伤口感染（RR=0.63；95%CI：[0.13，3.16]；P=0.57），血清或血肿（RR=3.00;95%CI：[0.49,18.55];P=0.24）。
■我们的研究结果表明，甲状腺切除术期间颈阔肌层闭合可能会导致术后疼痛增加，但不会显著影响瘢痕结局或术后并发症。
■在线版本包含补充材料，可在10.1007/s12070-024-04503-3获得。
