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Abstract：
Background Liver surgery is a major and challenging procedure for the surgeon, the anesthetist, and the patient. The objective of this study was to evaluate the postoperative nonhepatic complications of patients undergoing liver resection surgery with perioperative factors. Methods We retrospectively analyzed 79 patients who underwent liver resection surgeries at the Shaukat Khanum Memorial Cancer Hospital and Research Centre in Lahore, Pakistan, from July 2015 to December 2022. Results The mean age at the time of surgery was 53 years (range: 3-77 years), and the mean BMI was 26.43 (range: 15.72-38.0 kg/m2). Of the total patients, 44.3 % (n = 35) had no comorbidities, 26.6% (n=21) had one comorbidity, and 29.1% (n=23) had two or more comorbidities. Patients in whom the blood loss was more than 375 ml required postoperative oxygen inhalation with a significant relative risk of 2.6 (p=0.0392) and an odds ratio of 3.5 (p=0.0327). Similarly, patients who had a surgery time of more than five hours stayed in the hospital for more than seven days, with a statistically significant relative risk of 2.7 (p=0.0003) and odds ratio of 7.64 (p=0.0001). The duration of surgery was also linked with the possibility of requiring respiratory support, with a relative risk of 5.0 (p=0.0134) and odds ratio of 5.73 (p=0.1190). Conclusion Patients in our cohort who had a prolonged duration of surgery received an increased amount of fluids, and a large volume of blood loss was associated with prolonged stay in the ICU (>2 days), hospital admission (>7 days), ICU readmission, and increased incidence of cardiorespiratory, neurological, and renal disturbances postoperatively.
摘要：
背景对于外科医生来说，肝脏手术是一项主要且具有挑战性的手术，麻醉师,还有病人.本研究的目的是评估围手术期因素对肝切除术患者术后非肝并发症的影响。方法回顾性分析在拉合尔ShaukatKhanum纪念肿瘤医院和研究中心接受肝切除手术的79例患者，巴基斯坦,从2015年7月到2022年12月。结果手术时的平均年龄为53岁（范围：3-77岁），平均BMI为26.43（范围：15.72-38.0kg/m2）。在所有患者中，44.3%(n=35)没有合并症，26.6%(n=21)有一种共病，29.1%(n=23)有两种或两种以上合并症。失血量超过375ml的患者需要术后吸氧，相对风险为2.6（p=0.0392），比值比为3.5（p=0.0327）。同样，手术时间超过五个小时的病人在医院住了七天以上，统计学上显著的相对危险度为2.7(p=0.0003),比值比为7.64(p=0.0001).手术的持续时间也与需要呼吸支持的可能性有关，相对危险度为5.0（p=0.0134），比值比为5.73（p=0.1190）。结论我们队列中手术时间延长的患者接受的液体量增加，大量失血与ICU住院时间延长（>2天）有关，入院（>7天），ICU再入院,心肺疾病的发病率增加，神经学,和术后肾脏紊乱。
