关键词: Diagnostic discordance secondary opinion telepathology whole slide imaging

来  源:   DOI:10.4103/jpbs.jpbs_1042_23   PDF(Pubmed)

Abstract:
UNASSIGNED: histopathology plays a pivotal role in clinical diagnosis, research, and medical education. In recent years, whole slide imaging (wsi) has emerged as a potential alternative to traditional microscopy for pathological examination. This study aims to provide a comprehensive comparison of wsi and traditional microscopy(tm) in various aspects of histopathology practice.
UNASSIGNED: In this study, total of 30 cases comprising of oral premalignant and malignant cases which were diagnostically challenging was considered from the archives of the institute for validation. The slides were scanned with slide scanner and were evaluated by histopathologists. The comparative parameters which were noted were diagnostic discordances, number of fields observed to reach the diagnosis and time taken.
UNASSIGNED: The mean time taken by the pathologists to reach the diagnosis was significantly less in whole slide imaging technique. The average number of fields observed was higher by using wsi that too in a lesser time compared to tm, the results were found to be statistically significant with p=0.001.however the diagnostic disparity were seen to be maximum for verrucous lesions both in wsi and tm.
UNASSIGNED: wsi has facilitated the specialty with rapid mode of diagnosis in a more efficient and error less manner. It has also aided in case banking as well as research possibilities. Hence with the advent of telepathology it is very much necessary to get trained with wsi as early as possible so that the professionals can render correct diagnosis.
摘要:
组织病理学在临床诊断中起着举足轻重的作用,研究,和医学教育。近年来,全载玻片成像(wsi)已成为替代传统显微镜进行病理检查的潜在方法.本研究旨在提供wsi和传统显微镜(tm)在组织病理学实践的各个方面的综合比较。
在这项研究中,从研究所的档案中考虑了总共30例具有诊断挑战性的口腔癌前和恶性肿瘤病例进行验证。用载玻片扫描仪扫描载玻片并由组织病理学家评估。注意到的比较参数是诊断不一致,观察到的达到诊断的字段数量和花费的时间。
在整个载玻片成像技术中,病理学家达到诊断所需的平均时间明显较少。与tm相比,使用wsi在较短的时间内观察到的场的平均数量更高,结果具有统计学意义,p=0.001.然而,对于wsi和tm的疣状病变,诊断差异最大。
wsi以更有效和更少错误的方式促进了快速诊断模式的专业。它还帮助了银行和研究的可能性。因此,随着心灵感应病理学的出现,非常有必要尽早接受wsi培训,以便专业人员能够做出正确的诊断。
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