关键词: Andrographis paniculata and Rosa formulation antibacterial agent eco-friendly novel formulation urinary tract pathogens

来  源:   DOI:10.4103/jpbs.jpbs_574_23   PDF(Pubmed)

Abstract:
Andrographis Paniculata also known as the \"King of Bitters\" is a herbal medicine of the Acanthaceae family which is native to India and Sri Lanka. Andrographis Paniculata is a very useful medicinal plant as it has antioxidant, antidiabetic, antipyretic, anticancer properties. The main antibacterial activity of Andrographis Paniculata is due to the presence of andrographolide and arabinogalactan proteins. The medicinal properties of rose are mostly due to their abundance in phenolic compounds. They have many pharmacological properties like antibacterial, antioxidant, thrombolytic, and anticancer properties. The hips of the rose plant have Vitamin C in a concentration that is three times more than a citrus fruit that can be used in the treatment of a flu or a cold. Mueller-Hinton agar was utilized for this activity to determine the zone of inhibition. The plant extracts with different concentrations were loaded, and the plates were incubated for 24 hours at 37°C. After the incubation time, the zone of inhibition was measured. The results of this study are significant because they demonstrate the antibacterial activity of Andrographis Paniculata and Rosa against three bacterial pathogens. This suggests that the formulation of Andrographis Paniculata and Rosa has potential as a natural antibacterial agent. Further studies are needed to explore the mechanism of action and potential applications of this formulation. In conclusion, the study shows that the formulation of Andrographis Paniculata and Rosa has significant antibacterial activity against Klebsiella, Escherichia Coli, and Enterococcus Faecalis. This suggests that the formulation of Andrographis Paniculata and Rosa has potential as a natural antibacterial agent that could be further explored for its potential use in the treatment of bacterial infections.
摘要:
穿心莲也被称为“苦王”是一种原产于印度和斯里兰卡的刺科草药。穿心莲是一种非常有用的药用植物,因为它具有抗氧化剂,抗糖尿病药,退烧药,抗癌特性。穿心莲的主要抗菌活性是由于穿心莲内酯和阿拉伯半乳聚糖蛋白的存在。玫瑰的药用特性主要是由于它们富含酚类化合物。它们具有许多药理特性,如抗菌,抗氧化剂,溶栓剂,和抗癌特性。玫瑰植物的臀部含有维生素C,其浓度是柑橘类水果的三倍,可用于治疗流感或感冒。Mueller-Hinton琼脂用于该活性以确定抑制区。加载不同浓度的植物提取物,将板在37°C孵育24小时。孵化时间过后,测量抑制区。这项研究的结果是重要的,因为它们证明了穿心莲和罗莎对三种细菌病原体的抗菌活性。这表明穿心莲和罗莎的制剂具有作为天然抗菌剂的潜力。需要进一步研究以探索该制剂的作用机制和潜在应用。总之,研究表明,穿心莲和罗莎的配方对克雷伯菌具有显著的抗菌活性,大肠杆菌,和粪肠球菌.这表明穿心莲和罗莎的制剂具有作为天然抗菌剂的潜力,可以进一步探索其在治疗细菌感染中的潜在用途。
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