PDF(Pubmed)
Abstract：
Nano-coating of orthodontic brackets with a combination or hybrid of metals and metal oxides may reduce the streptococcus mutans count and incidence of enamel decalcification seen around brackets in patients undergoing fixed orthodontic treatment. In total, 255 orthodontic brackets (3M Unitek, Monrovia, California, USA) were divided into one control group (group I) of 60 and three experimental groups of 65 each (groups II, III, and IV). The experimental group brackets were coated with a combination of silver-zinc oxide, copper oxide -zinc oxide, and silver-copper oxide nanoparticles using physical vapour deposition method. The two nanoparticles used for each group were mixed in the ratio of 1:1 by weight for providing a uniform hybrid coating. Sixty brackets from each group were used for microbiological evaluation of antibacterial activity against Streptococcus mutans in blood agar medium, and the remaining five brackets from each experimental group were used for SEM analysis to check the uniformity of the coating. Nano-coated brackets demonstrated better antibacterial properties than uncoated brackets. Copper oxide-zinc oxide nanoparticles coated brackets demonstrated better antibacterial properties than the silver-zinc oxide and silver- copper oxide coated brackets.
摘要：
用金属和金属氧化物的组合或混合对正畸托槽进行纳米涂层可以减少接受固定正畸治疗的患者在托槽周围可见的变形链球菌计数和牙釉质脱钙的发生率。总的来说,255正畸托槽（3MUnitek，蒙罗维亚,加州,USA）分为一个对照组（I组）60和三个实验组65（II组，III,andIV).实验组托槽涂有银氧化锌的组合，氧化铜-氧化锌，和银-铜氧化物纳米颗粒采用物理气相沉积法。用于每组的两种纳米颗粒以1:1的重量比混合,以提供均匀的混合涂层。每组60个支架用于微生物学评估在血琼脂培养基中对变异链球菌的抗菌活性，每个实验组的其余五个支架用于SEM分析，以检查涂层的均匀性。纳米涂层支架表现出比未涂层支架更好的抗菌性能。氧化铜-氧化锌纳米颗粒涂覆的托槽表现出比银-氧化锌和银-氧化铜涂覆的托槽更好的抗菌性能。
