PDF(Pubmed)
Abstract：
UNASSIGNED: Intimate partner violence (IPV) perpetration is highly prevalent among veterans. Suggested risk factors of IPV perpetration include combat exposure, post-traumatic stress disorder (PTSD), depression, alcohol use, and mild traumatic brain injury (mTBI). While the underlying brain pathophysiological characteristics associated with IPV perpetration remain largely unknown, previous studies have linked aggression and violence to alterations of the limbic system. Here, we investigate whether IPV perpetration is associated with limbic microstructural abnormalities in military veterans. Further, we test the effect of potential risk factors (i.e., PTSD, depression, substance use disorder, mTBI, and war zone-related stress) on the prevalence of IPV perpetration.
UNASSIGNED: Structural and diffusion-weighted magnetic resonance imaging (dMRI) data were acquired from 49 male veterans of the Iraq and Afghanistan wars (Operation Enduring Freedom/Operation Iraqi Freedom; OEF/OIF) of the Translational Research Center for TBI and Stress Disorders (TRACTS) study. IPV perpetration was assessed using the psychological aggression and physical assault sub-scales of the Revised Conflict Tactics Scales (CTS2). Odds ratios were calculated to assess the likelihood of IPV perpetration in veterans with either of the following diagnoses: PTSD, depression, substance use disorder, or mTBI. Fractional anisotropy tissue (FA) measures were calculated for limbic gray matter structures (amygdala-hippocampus complex, cingulate, parahippocampal gyrus, entorhinal cortex). Partial correlations were calculated between IPV perpetration, neuropsychiatric symptoms, and FA.
UNASSIGNED: Veterans with a diagnosis of PTSD, depression, substance use disorder, or mTBI had higher odds of perpetrating IPV. Greater war zone-related stress, and symptom severity of PTSD, depression, and mTBI were significantly associated with IPV perpetration. CTS2 (psychological aggression), a measure of IPV perpetration, was associated with higher FA in the right amygdala-hippocampus complex (r = 0.400, p = 0.005).
UNASSIGNED: Veterans with psychiatric disorders and/or mTBI exhibit higher odds of engaging in IPV perpetration. Further, the more severe the symptoms of PTSD, depression, or TBI, and the greater the war zone-related stress, the greater the frequency of IPV perpetration. Moreover, we report a significant association between psychological aggression against an intimate partner and microstructural alterations in the right amygdala-hippocampus complex. These findings suggest the possibility of a structural brain correlate underlying IPV perpetration that requires further research.
UNASSIGNED: Structural and diffusion-weighted magnetic resonance imaging (dMRI) data were acquired from 49 male veterans of the Iraq and Afghanistan wars (Operation Enduring Freedom/Operation Iraqi Freedom; OEF/OIF) of the Translational Research Center for TBI and Stress Disorders (TRACTS) study. IPV perpetration was assessed using the psychological aggression and physical assault sub-scales of the Revised Conflict Tactics Scales (CTS2). Odds ratios were calculated to assess the likelihood of IPV perpetration in veterans with either of the following diagnoses: PTSD, depression, substance use disorder, or mTBI. Fractional anisotropy tissue (FA) measures were calculated for limbic gray matter structures (amygdala-hippocampus complex, cingulate, parahippocampal gyrus, entorhinal cortex). Partial correlations were calculated between IPV perpetration, neuropsychiatric symptoms, and FA.
UNASSIGNED: Veterans with a diagnosis of PTSD, depression, substance use disorder, or mTBI had higher odds of perpetrating IPV. Greater war zone-related stress, and symptom severity of PTSD, depression, and mTBI were significantly associated with IPV perpetration. CTS2 (psychological aggression), a measure of IPV perpetration, was associated with higher FA in the right amygdala-hippocampus complex (r = 0.400, p = 0.005).
UNASSIGNED: Veterans with psychiatric disorders and/or mTBI exhibit higher odds of engaging in IPV perpetration. Further, the more severe the symptoms of PTSD, depression, or TBI, and the greater the war zone-related stress, the greater the frequency of IPV perpetration. Moreover, we report a significant association between psychological aggression against an intimate partner and microstructural alterations in the right amygdala-hippocampus complex. These findings suggest the possibility of a structural brain correlate underlying IPV perpetration that requires further research.
摘要：
■亲密伴侣暴力（IPV）在退伍军人中非常普遍。建议的IPV危险因素包括战斗暴露，创伤后应激障碍（PTSD），抑郁症,酒精使用,和轻度创伤性脑损伤（mTBI）。虽然与IPV感染相关的潜在脑部病理生理特征在很大程度上仍然未知，先前的研究将侵略和暴力与边缘系统的改变联系起来。这里,我们调查了退伍军人的IPV感染是否与边缘微结构异常相关.Further,我们测试潜在风险因素的影响(即，创伤后应激障碍,抑郁症,物质使用障碍,mTBI,和与战区相关的压力)对IPV流行的影响。
■结构和扩散加权磁共振成像（dMRI）数据来自TBI和应激障碍转化研究中心（TRACTS）研究的49名伊拉克和阿富汗战争（持久自由行动/伊拉克自由行动；OEF/OIF）的男性退伍军人。使用修订的冲突战术量表（CTS2）的心理侵略和人身攻击子量表评估IPV的发生率。计算赔率以评估具有以下任一诊断的退伍军人IPV发生的可能性：PTSD，抑郁症,物质使用障碍,或者mTBI.计算边缘灰质结构（杏仁核-海马复合体，扣带回,海马旁回,内嗅皮层）。计算了IPV穿透率之间的偏相关，神经精神症状,和FA。
■诊断为PTSD的退伍军人，抑郁症,物质使用障碍,或mTBI有较高的发生IPV的几率。更大的战区相关压力，和创伤后应激障碍的症状严重程度，抑郁症,mTBI与IPV感染显著相关。CTS2（心理攻击），一种IPV行为的衡量标准，与右杏仁核-海马复合体中更高的FA相关(r=0.400,p=0.005)。
■患有精神疾病和/或mTBI的退伍军人参与IPV的几率更高。Further,创伤后应激障碍的症状越严重，抑郁症,或TBI，与战区有关的压力越大，IPV渗透的频率越大。此外，我们报道了对亲密伴侣的心理攻击与右侧杏仁核-海马复合体的微结构改变之间的显著关联.这些发现表明，大脑结构可能与潜在的IPV行为相关，需要进一步研究。
■结构和扩散加权磁共振成像（dMRI）数据来自TBI和应激障碍转化研究中心（TRACTS）研究的49名伊拉克和阿富汗战争（持久自由行动/伊拉克自由行动；OEF/OIF）的男性退伍军人。使用修订的冲突战术量表（CTS2）的心理侵略和人身攻击子量表评估IPV的发生率。计算赔率以评估具有以下任一诊断的退伍军人IPV发生的可能性：PTSD，抑郁症,物质使用障碍,或者mTBI.计算边缘灰质结构（杏仁核-海马复合体，扣带回,海马旁回,内嗅皮层）。计算了IPV穿透率之间的偏相关，神经精神症状,和FA。
■诊断为PTSD的退伍军人，抑郁症,物质使用障碍,或mTBI有较高的发生IPV的几率。更大的战区相关压力，和创伤后应激障碍的症状严重程度，抑郁症,mTBI与IPV感染显著相关。CTS2（心理攻击），一种IPV行为的衡量标准，与右杏仁核-海马复合体中更高的FA相关(r=0.400,p=0.005)。
■患有精神疾病和/或mTBI的退伍军人参与IPV的几率更高。Further,创伤后应激障碍的症状越严重，抑郁症,或TBI，与战区有关的压力越大，IPV渗透的频率越大。此外，我们报道了对亲密伴侣的心理攻击与右侧杏仁核-海马复合体的微结构改变之间的显著关联.这些发现表明，大脑结构可能与潜在的IPV行为相关，需要进一步研究。
