PDF(Pubmed)
Abstract：
UNASSIGNED: Renal arteriovenous malformations (rAVMs) are congenital abnormal pathways between renal arteries and veins that are rare in the general population. It is often misdiagnosed as malignant renal tumors with abundant blood supply, and the definitive diagnosis primarily relies on angiography. Multimodality imaging, including contrast-enhanced computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET)/CT plays an important role in the differential diagnosis of renal space-occupying lesions.
UNASSIGNED: A 56-year-old man presented with abdominal distension, loss of appetite, and back pain without obvious cause 2 years ago, without nausea vomiting, or frequent urination. Gastroscopy and colonoscopy showed multiple polyps in the duodenum and colon. Abdomen contrast-enhanced CT revealed a mass of 1.6 × 1.4 cm in the left kidney, which was considered to be a malignant tumor. PET/CT was performed for further diagnosis; the 18F-fluorodesoxyglucose (18F-FDG) PET/CT scan showed mild uptake in the left renal mass, while no uptake of 18F- prostate-specific membrane antigen (PSMA) was observed. Following a multidisciplinary discussion, the possibility of renal AVMs was considered and subsequently confirmed by renal angiography as the diagnosis. Then, selective segmental renal artery embolization was performed for treatment.
UNASSIGNED: Renal AVMs are extremely rare in clinical practice. Due to limited research on the application of 18F-FDG and 18F-PSMA PET/CT to renal AVMs, its role remains largely unexplored. With the increasing popularity of PET/CT imaging, comprehensive imaging of the disease has become indispensable. We report the first case of PSMA PET/CT imaging in renal AVMs, and when PSMA expression is absent in a renal mass, the possibility of renal AVMs should be considered.
UNASSIGNED: A 56-year-old man presented with abdominal distension, loss of appetite, and back pain without obvious cause 2 years ago, without nausea vomiting, or frequent urination. Gastroscopy and colonoscopy showed multiple polyps in the duodenum and colon. Abdomen contrast-enhanced CT revealed a mass of 1.6 × 1.4 cm in the left kidney, which was considered to be a malignant tumor. PET/CT was performed for further diagnosis; the 18F-fluorodesoxyglucose (18F-FDG) PET/CT scan showed mild uptake in the left renal mass, while no uptake of 18F- prostate-specific membrane antigen (PSMA) was observed. Following a multidisciplinary discussion, the possibility of renal AVMs was considered and subsequently confirmed by renal angiography as the diagnosis. Then, selective segmental renal artery embolization was performed for treatment.
UNASSIGNED: Renal AVMs are extremely rare in clinical practice. Due to limited research on the application of 18F-FDG and 18F-PSMA PET/CT to renal AVMs, its role remains largely unexplored. With the increasing popularity of PET/CT imaging, comprehensive imaging of the disease has become indispensable. We report the first case of PSMA PET/CT imaging in renal AVMs, and when PSMA expression is absent in a renal mass, the possibility of renal AVMs should be considered.
摘要：
■肾动静脉畸形（rAVM）是肾动脉和静脉之间的先天性异常通路，在普通人群中很少见。常被误诊为血液供应丰富的肾脏恶性肿瘤，而最终的诊断主要依靠血管造影.多模态成像,包括对比增强计算机断层扫描（CT），磁共振成像（MRI），正电子发射断层扫描（PET）/CT在肾脏占位性病变的鉴别诊断中起着重要作用。
■一名56岁男子出现腹胀,食欲不振,2年前没有明显原因的背痛，没有恶心呕吐，或尿频。胃镜和结肠镜检查显示十二指肠和结肠多发息肉。腹部增强CT显示左肾肿块1.6×1.4cm，被认为是恶性肿瘤.进行PET/CT进一步诊断；18F-氟脱氧葡萄糖（18F-FDG）PET/CT扫描显示左肾肿块轻度摄取，而未观察到18F-前列腺特异性膜抗原（PSMA）的摄取。经过多学科的讨论，我们考虑了肾AVM的可能性,随后通过肾动脉造影证实为诊断.然后，选择性肾段动脉栓塞治疗.
■肾AVM在临床实践中极为罕见。由于18F-FDG和18F-PSMAPET/CT在肾AVM中的应用研究有限，它的作用在很大程度上仍未被探索。随着PET/CT成像技术的日益普及,疾病的全面成像已成为不可或缺的。我们报告了第一例PSMAPET/CT显像在肾AVM中的应用，当肾脏肿块中缺乏PSMA表达时，应考虑肾AVM的可能性。
■一名56岁男子出现腹胀,食欲不振,2年前没有明显原因的背痛，没有恶心呕吐，或尿频。胃镜和结肠镜检查显示十二指肠和结肠多发息肉。腹部增强CT显示左肾肿块1.6×1.4cm，被认为是恶性肿瘤.进行PET/CT进一步诊断；18F-氟脱氧葡萄糖（18F-FDG）PET/CT扫描显示左肾肿块轻度摄取，而未观察到18F-前列腺特异性膜抗原（PSMA）的摄取。经过多学科的讨论，我们考虑了肾AVM的可能性,随后通过肾动脉造影证实为诊断.然后，选择性肾段动脉栓塞治疗.
■肾AVM在临床实践中极为罕见。由于18F-FDG和18F-PSMAPET/CT在肾AVM中的应用研究有限，它的作用在很大程度上仍未被探索。随着PET/CT成像技术的日益普及,疾病的全面成像已成为不可或缺的。我们报告了第一例PSMAPET/CT显像在肾AVM中的应用，当肾脏肿块中缺乏PSMA表达时，应考虑肾AVM的可能性。
