PDF(Pubmed)
Abstract：
UNASSIGNED: Recent advances in imaging methods increased the incidental detection of small renal angiomyolipoma (AML). However, guidelines for managing small AML are lacking, and decisions about imaging frequency and timing of intervention are made on an individual basis. This study aims to investigate the clinical behavior of small sporadic AML and propose an optimal follow-up strategy.
UNASSIGNED: The study is a retrospective analysis of 168 individuals who had hyperechoic lesions, suggestive of AML detected during abdominal ultrasound as a part of their health checkup. The clinical information of the individuals, including tumor characteristics and renal function, was reviewed. Statistical analysis was performed to identify factors associated with tumor growth and renal function.
UNASSIGNED: Most AMLs were small (≤20 mm) and did not exhibit malignant characteristics. The tumors showed a slow growth rate, with a mean growth rate of 0.24 mm/year. Only a small proportion of cases (1.2%) required intervention due to significant enlargement. Factors such as tumor size and gender were not significantly associated with tumor growth rate or renal function. However, younger patients showed a higher tumor growth rate and a more pronounced decline in renal function.
UNASSIGNED: Small sporadic AMLs have a slow growth rate and little risk of malignancy. Neither tumor size nor gender was predictive factors for tumor growth or renal function. Nevertheless, close monitoring of tumor growth and renal function is advised, particularly in younger patients. This study highlights the need for further research and guidelines to establish an optimal surveillance protocol for small AMLs.
UNASSIGNED: The study is a retrospective analysis of 168 individuals who had hyperechoic lesions, suggestive of AML detected during abdominal ultrasound as a part of their health checkup. The clinical information of the individuals, including tumor characteristics and renal function, was reviewed. Statistical analysis was performed to identify factors associated with tumor growth and renal function.
UNASSIGNED: Most AMLs were small (≤20 mm) and did not exhibit malignant characteristics. The tumors showed a slow growth rate, with a mean growth rate of 0.24 mm/year. Only a small proportion of cases (1.2%) required intervention due to significant enlargement. Factors such as tumor size and gender were not significantly associated with tumor growth rate or renal function. However, younger patients showed a higher tumor growth rate and a more pronounced decline in renal function.
UNASSIGNED: Small sporadic AMLs have a slow growth rate and little risk of malignancy. Neither tumor size nor gender was predictive factors for tumor growth or renal function. Nevertheless, close monitoring of tumor growth and renal function is advised, particularly in younger patients. This study highlights the need for further research and guidelines to establish an optimal surveillance protocol for small AMLs.
摘要：
■成像方法的最新进展增加了对小肾血管平滑肌脂肪瘤（AML）的偶然检测。然而,缺乏管理小型AML的指导方针，关于成像频率和干预时间的决定是在个人基础上做出的。本研究旨在调查小型散发性AML的临床行为，并提出最佳的随访策略。
■该研究是对168名患有高回声病变的个体的回顾性分析，提示在腹部超声检查中检测到AML，作为他们健康检查的一部分。个体的临床信息，包括肿瘤特征和肾功能，已审查。进行统计分析以确定与肿瘤生长和肾功能相关的因素。
■大多数AMLs小（≤20mm），没有恶性特征。肿瘤生长速度缓慢,平均增长率为0.24毫米/年。只有一小部分病例（1.2％）由于大幅扩大而需要干预。肿瘤大小和性别等因素与肿瘤生长速度和肾功能无显著相关性。然而,年轻患者显示出更高的肿瘤生长速率和更明显的肾功能下降。
■小的散发性AMLs生长速度缓慢，恶性肿瘤的风险很小。肿瘤大小和性别都不是肿瘤生长或肾功能的预测因素。然而，建议密切监测肿瘤生长和肾功能，尤其是年轻患者。这项研究强调了进一步研究和指南的必要性，以建立针对小型AMLs的最佳监测方案。
■该研究是对168名患有高回声病变的个体的回顾性分析，提示在腹部超声检查中检测到AML，作为他们健康检查的一部分。个体的临床信息，包括肿瘤特征和肾功能，已审查。进行统计分析以确定与肿瘤生长和肾功能相关的因素。
■大多数AMLs小（≤20mm），没有恶性特征。肿瘤生长速度缓慢,平均增长率为0.24毫米/年。只有一小部分病例（1.2％）由于大幅扩大而需要干预。肿瘤大小和性别等因素与肿瘤生长速度和肾功能无显著相关性。然而,年轻患者显示出更高的肿瘤生长速率和更明显的肾功能下降。
■小的散发性AMLs生长速度缓慢，恶性肿瘤的风险很小。肿瘤大小和性别都不是肿瘤生长或肾功能的预测因素。然而，建议密切监测肿瘤生长和肾功能，尤其是年轻患者。这项研究强调了进一步研究和指南的必要性，以建立针对小型AMLs的最佳监测方案。
