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Abstract：
The present case report is aimed to highlight the difficulty and the reason for the delayed diagnosis of phosphaturic mesenchymal tumors, emphasizing the need of standardized protocols for diagnosis, surgery and follow-up in high-volume hospitals. The clinical signs and symptoms, diagnostic and therapeutic procedures, immunohistological features were analyzed. Delayed diagnosis of phosphaturic mesenchymal tumor was primarily due to non-specific clinical symptoms such as fatigue, muscular and bone pain, and multiple fractures. This cryptic clinical picture made the diagnosis tricky that led to treatment of patient for non-specific pain and stress fractures before to consider the tumor-induced osteomalacia syndrome. Some well-documented studies were found in the literature in which the history of trauma is a critical trigger of glomus tumors. Extra-subungual tumors most frequently occur in the knee and ankle regions, particularly among young adults, and the diagnosis is typically made approximately 7.2 years after initial symptom onset. The difficult tumor localization represented an additional obstacle to the prompt treatment, leading to delayed curative surgery.
摘要：
本病例报告旨在强调磷性间充质肿瘤诊断延迟的困难和原因。强调需要标准化的诊断方案，在大批量医院进行手术和随访。临床症状和体征,诊断和治疗程序，分析了免疫组织学特征。磷性间充质肿瘤的延迟诊断主要是由于非特异性的临床症状，如疲劳，肌肉和骨骼疼痛，和多处骨折.这种隐秘的临床表现使诊断变得棘手，导致在考虑肿瘤诱导的骨软化症综合征之前，需要对患者进行非特异性疼痛和应力性骨折的治疗。在文献中发现了一些有据可查的研究，其中创伤史是血管球瘤的关键触发因素。甲下肿瘤最常见于膝关节和踝区。特别是在年轻人中，诊断通常在最初症状发作后约7.2年进行。困难的肿瘤定位代表了及时治疗的额外障碍，导致手术治疗延迟。
