PDF(Pubmed)
Abstract：
UNASSIGNED: Shear wave elastography (SWE) is a novel imaging technique that provides quantitative assessments of tissue stiffness. This non-invasive method offers real-time, quantitative measurements and has been widely applied to various tissues, providing valuable diagnostic insights.
UNASSIGNED: This study aimed to investigate the feasibility of using SWE to evaluate the stiffness of the lens in patients with age-related cataracts.
UNASSIGNED: A comparative analysis involving 92 patients diagnosed with age-related cataracts and 39 healthy controls was conducted. Lens stiffness was quantified using SWE measurements. The lens nucleus of all participants was graded based on the Lens Opacities Classification System II (LOCS II). Correlations between the stiffness of the lens and age were also analyzed.
UNASSIGNED: The study indicates that both the stiffness of the lens and the lens nucleus were significantly higher in patients with age-related cataracts compared to healthy controls (P < 0.001). In patients with age-related cataracts, although lens nucleus stiffness variations across different grades of cataract severity were not statistically significant, all grades displayed increased stiffness relative to healthy controls. Additionally, a significant positive correlation between lens stiffness and age was observed in all participants (P < 0.001).
UNASSIGNED: SWE appears to be a promising imaging technique for quantitatively assessing the mechanical characteristics of the lens in patients with age-related cataracts.
UNASSIGNED: This study aimed to investigate the feasibility of using SWE to evaluate the stiffness of the lens in patients with age-related cataracts.
UNASSIGNED: A comparative analysis involving 92 patients diagnosed with age-related cataracts and 39 healthy controls was conducted. Lens stiffness was quantified using SWE measurements. The lens nucleus of all participants was graded based on the Lens Opacities Classification System II (LOCS II). Correlations between the stiffness of the lens and age were also analyzed.
UNASSIGNED: The study indicates that both the stiffness of the lens and the lens nucleus were significantly higher in patients with age-related cataracts compared to healthy controls (P < 0.001). In patients with age-related cataracts, although lens nucleus stiffness variations across different grades of cataract severity were not statistically significant, all grades displayed increased stiffness relative to healthy controls. Additionally, a significant positive correlation between lens stiffness and age was observed in all participants (P < 0.001).
UNASSIGNED: SWE appears to be a promising imaging technique for quantitatively assessing the mechanical characteristics of the lens in patients with age-related cataracts.
摘要：
■剪切波弹性成像（SWE）是一种新颖的成像技术，可对组织硬度进行定量评估。这种非侵入性方法提供了实时，定量测量，并已广泛应用于各种组织，提供有价值的诊断见解。
■本研究旨在探讨使用SWE评估年龄相关性白内障患者晶状体硬度的可行性。
■对92名诊断为年龄相关性白内障的患者和39名健康对照者进行了比较分析。使用SWE测量来量化透镜刚度。根据晶状体不透明度分类系统II（LOCSII）对所有参与者的晶状体核进行分级。还分析了晶状体刚度与年龄之间的相关性。
■研究表明，与年龄相关的白内障患者的晶状体硬度和晶状体核的硬度均明显高于健康对照组（P<0.001）。年龄相关性白内障患者,尽管不同级别白内障严重程度的晶状体核硬度差异无统计学意义，所有等级均显示相对于健康对照的刚度增加.此外,在所有参与者中观察到晶状体硬度与年龄之间的显著正相关(P<0.001).
■SWE似乎是一种有前途的成像技术，用于定量评估年龄相关性白内障患者晶状体的机械特性。
■本研究旨在探讨使用SWE评估年龄相关性白内障患者晶状体硬度的可行性。
■对92名诊断为年龄相关性白内障的患者和39名健康对照者进行了比较分析。使用SWE测量来量化透镜刚度。根据晶状体不透明度分类系统II（LOCSII）对所有参与者的晶状体核进行分级。还分析了晶状体刚度与年龄之间的相关性。
■研究表明，与年龄相关的白内障患者的晶状体硬度和晶状体核的硬度均明显高于健康对照组（P<0.001）。年龄相关性白内障患者,尽管不同级别白内障严重程度的晶状体核硬度差异无统计学意义，所有等级均显示相对于健康对照的刚度增加.此外,在所有参与者中观察到晶状体硬度与年龄之间的显著正相关(P<0.001).
■SWE似乎是一种有前途的成像技术，用于定量评估年龄相关性白内障患者晶状体的机械特性。
