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Abstract：
Purpose To evaluate clinical outcomes of primary pterygium excision surgery and analyze risk factors for pterygium recurrence. Setting Eye Treatment Centre, Cornea and External Diseases Service, Whipps Cross Hospital, London, United Kingdom. Methods Retrospective case series of eyes undergoing primary pterygium excision between August 2017 and July 2022. Patients who underwent \"pterygium excision\" documented in the electronic patient record system were identified. Patients with recurrent pterygium and those lost-to-follow-up were excluded. The duration of follow-up, type of surgery performed (primary conjunctival closure, conjunctival autograft, and amniotic membrane transplantation), recurrences with respect to the type of surgery performed, and postoperative complications were collected and analyzed. Results In total, 83 eyes (from 79 patients) were included. The mean age of our patient cohort was 59.3 ± 5.9 years. The most common ethnic distribution was Black Caribbean (15.7%). Conjunctival autograft was performed in 76 eyes (91.6%), primary conjunctival closure was performed in five eyes (6%) and amniotic membrane transplantation was performed in two eyes (2.4%). The recurrence rate with conjunctival autograft was 1.3% with a median time to recurrence of 2.98 months. Recurrence was significantly more common in patients below the age of 40 years (p=0.03). Recurrence was not significantly associated with gender (p=0.23), ethnicity (p=0.17), or grade of surgeon (p=0.38). Conclusion Our findings demonstrate the effectiveness of conjunctival autograft with fibrin glue fixation for the surgical management of primary pterygium. Recurrence was found to be significantly more common in patients under the age of 40 years old. However, recurrence was not associated with ethnicity, gender, or surgeon grade.
摘要：
目的评价原发性翼状胬肉切除手术的临床疗效,分析翼状胬肉复发的危险因素。设置眼部治疗中心，角膜和外部疾病服务，WhippsCross医院,伦敦,联合王国。方法回顾性分析2017年8月至2022年7月行原发性翼状胬肉切除术的病例系列。确定了电子病历系统中记录的接受“翼状胬肉切除术”的患者。复发性翼状胬肉和失访的患者被排除在外。随访的持续时间，进行的手术类型（原发性结膜闭合，自体结膜移植,和羊膜移植），复发的类型的手术，收集并分析术后并发症。结果总计,包括83只眼（来自79例患者）。我们的患者队列的平均年龄为59.3±5.9岁。最常见的种族分布是黑加勒比（15.7％）。结膜自体移植76眼(91.6%),5只眼(6%)进行原发性结膜闭合,2只眼(2.4%)进行羊膜移植.自体结膜移植的复发率为1.3％，中位复发时间为2.98个月。复发在40岁以下的患者中更为常见（p=0.03）。复发与性别无关（p=0.23），种族（p=0.17），或级别的外科医生（p=0.38）。结论我们的研究结果证明了结膜自体移植结合纤维蛋白胶固定在原发性翼状胬肉手术治疗中的有效性。发现复发在40岁以下的患者中明显更常见。然而,复发与种族无关,性别,或外科医生等级。
